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. 2022 Jul 26;9(8):ofac375.
doi: 10.1093/ofid/ofac375. eCollection 2022 Aug.

Clinical Features and Treatment Outcomes of Pulmonary Mycobacterium avium-intracellulare Complex With and Without Coinfections

Grace Wang  1 , Jack T Stapleton  2 , Arthur W Baker  3 , Nadine Rouphael  4 , C Buddy Creech  5 , Hana M El Sahly  6 , Jason E Stout  3 , Lisa Jackson  7 , Edward Charbek  1 , Francisco J Leyva  8 , Kay M Tomashek  8 , Melinda Tibbals  8 , Aaron Miller  1 , Sharon Frey  1 , Samson Niemotka  1 , Timothy L Wiemken  1 , Nour Beydoun  4 , Ghina Alaaeddine  4 , Nicholas Turner  3 , Emmanuel B Walter  3 , Robin Chamberland  9 , Getahun Abate  1
Affiliations

Clinical Features and Treatment Outcomes of Pulmonary Mycobacterium avium-intracellulare Complex With and Without Coinfections

Grace Wang et al. Open Forum Infect Dis. .

Abstract

Coinfections are more common in patients with cystic fibrosis and bronchiectasis. Infiltrates on imaging studies are seen more commonly in patients with coinfections, but coinfections did not affect treatment outcomes of pulmonary Mycobacterium avium complex.

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Figures

Figure 1.
Figure 1.
Flowchart of total health records reviewed and number of patients with pulmonary nontuberculous mycobacteria and pulmonary Mycobacterium avium complex (PMAC) with and without coinfection. Among those who were treated for PMAC, 71 without coinfection and 27 with coinfection had treatment outcome data available. Abbreviations: HIV, human immunodeficiency virus; MAC, Mycobacterium avium complex; PMAC, pulmonary Mycobacterium avium complex; PNTM, pulmonary nontuberculous mycobacteria.
Figure 2.
Figure 2.
Types of coinfections. Pseudomonas, Staphylococcus aureus, and Aspergillus were the most common coinfections.
See this image and copyright information in PMC

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