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. 2023 Feb;39(2):356-358.
doi: 10.1007/s12264-022-00940-8. Epub 2022 Aug 12.

PROK2-PROKR2 Signaling: New Contributor to Pleasant Touch

Feng-Lin Chen  1 , Hai-Yan Yin  1   2 , Yong Tang  3   4   5
Affiliations

PROK2-PROKR2 Signaling: New Contributor to Pleasant Touch

Feng-Lin Chen et al. Neurosci Bull. 2023 Feb.
No abstract available

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Figures

Fig. 1
Fig. 1
Cartoon showing the crucial role of the prokineticin receptor 2 (Prokr2)—prokineticin2 (Prok2) signaling pathway in pleasant touch sensation. PROK2, a neuropeptide, encodes and transmits pleasant touch sensation to spinal PROKR2 interneurons, which provides a peptidergic pathway from the skin to the spinal cord. PROK2 fibers that synapse with PROKR2+ neurons in lamina II of the spinal cord may be the equivalent of human unmyelinated C-tactile fibers
See this image and copyright information in PMC

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