Review

. 2022 Sep:237:154041.

doi: 10.1016/j.prp.2022.154041. Epub 2022 Jul 28.

Complementary tool in diagnosis of hydatidiform mole: Review

Affiliations

¹ Department of Pathology, Universidade Federal de São Paulo, Escola Paulista de Medicina, Botucatu Street, 740 - Vila Clementino, São Paulo, SP, Brazil; Laboratory of Molecular and Experimental Pathology, Universidade Federal de São Paulo, Escola Paulista de Medicina, Pedro de Toledo Street, 781, 5º floor - Vila Clementino, São Paulo, SP, Brazil. Electronic address: gaabi.marini@gmail.com.
² Department of Pathology, Universidade Federal de São Paulo, Escola Paulista de Medicina, Botucatu Street, 740 - Vila Clementino, São Paulo, SP, Brazil; Laboratory of Molecular and Experimental Pathology, Universidade Federal de São Paulo, Escola Paulista de Medicina, Pedro de Toledo Street, 781, 5º floor - Vila Clementino, São Paulo, SP, Brazil. Electronic address: andrezasf@gmail.com.
³ Department of Pathology, Universidade Federal de São Paulo, Escola Paulista de Medicina, Botucatu Street, 740 - Vila Clementino, São Paulo, SP, Brazil; Laboratory of Molecular and Experimental Pathology, Universidade Federal de São Paulo, Escola Paulista de Medicina, Pedro de Toledo Street, 781, 5º floor - Vila Clementino, São Paulo, SP, Brazil. Electronic address: debsalles@gmail.com.
⁴ Laboratory of Molecular and Experimental Pathology, Universidade Federal de São Paulo, Escola Paulista de Medicina, Pedro de Toledo Street, 781, 5º floor - Vila Clementino, São Paulo, SP, Brazil; Graduate student of Escola Paulista de Enfermagem, Universidade Federal de São Paulo, Napoleão de Barros Street, 754 - Vila Clementino, São Paulo, SP, Brazil. Electronic address: cslourenco@unifesp.br.
⁵ Laboratory of Molecular and Experimental Pathology, Universidade Federal de São Paulo, Escola Paulista de Medicina, Pedro de Toledo Street, 781, 5º floor - Vila Clementino, São Paulo, SP, Brazil. Electronic address: daribeiro@unifesp.br.
⁶ Department of Obstetrics, Universidade Federal de São Paulo, Escola Paulista de Medicina, Napoleão de Barros Street, 875 - Vila Clementino, São Paulo, SP, Brazil. Electronic address: sueysun@gmail.com.
⁷ Department of Pathology, Universidade Federal de São Paulo, Escola Paulista de Medicina, Botucatu Street, 740 - Vila Clementino, São Paulo, SP, Brazil; Laboratory of Molecular and Experimental Pathology, Universidade Federal de São Paulo, Escola Paulista de Medicina, Pedro de Toledo Street, 781, 5º floor - Vila Clementino, São Paulo, SP, Brazil. Electronic address: mms.ishigai@gmail.com.
⁸ Department of Pathology, Universidade Federal de São Paulo, Escola Paulista de Medicina, Botucatu Street, 740 - Vila Clementino, São Paulo, SP, Brazil; Laboratory of Molecular and Experimental Pathology, Universidade Federal de São Paulo, Escola Paulista de Medicina, Pedro de Toledo Street, 781, 5º floor - Vila Clementino, São Paulo, SP, Brazil. Electronic address: edna.iwamura@unifesp.br.
⁹ Department of Pathology, Universidade Federal de São Paulo, Escola Paulista de Medicina, Botucatu Street, 740 - Vila Clementino, São Paulo, SP, Brazil. Electronic address: mtsalves@unifesp.br.
¹⁰ Department of Pathology, Universidade Federal de São Paulo, Escola Paulista de Medicina, Botucatu Street, 740 - Vila Clementino, São Paulo, SP, Brazil; Laboratory of Molecular and Experimental Pathology, Universidade Federal de São Paulo, Escola Paulista de Medicina, Pedro de Toledo Street, 781, 5º floor - Vila Clementino, São Paulo, SP, Brazil. Electronic address: andreamoraesmalinverni@gmail.com.

PMID: 35961058
DOI: 10.1016/j.prp.2022.154041

Review

Complementary tool in diagnosis of hydatidiform mole: Review

Gabriela Marini Laviola et al. Pathol Res Pract. 2022 Sep.

. 2022 Sep:237:154041.

doi: 10.1016/j.prp.2022.154041. Epub 2022 Jul 28.

Affiliations

¹ Department of Pathology, Universidade Federal de São Paulo, Escola Paulista de Medicina, Botucatu Street, 740 - Vila Clementino, São Paulo, SP, Brazil; Laboratory of Molecular and Experimental Pathology, Universidade Federal de São Paulo, Escola Paulista de Medicina, Pedro de Toledo Street, 781, 5º floor - Vila Clementino, São Paulo, SP, Brazil. Electronic address: gaabi.marini@gmail.com.
² Department of Pathology, Universidade Federal de São Paulo, Escola Paulista de Medicina, Botucatu Street, 740 - Vila Clementino, São Paulo, SP, Brazil; Laboratory of Molecular and Experimental Pathology, Universidade Federal de São Paulo, Escola Paulista de Medicina, Pedro de Toledo Street, 781, 5º floor - Vila Clementino, São Paulo, SP, Brazil. Electronic address: andrezasf@gmail.com.
³ Department of Pathology, Universidade Federal de São Paulo, Escola Paulista de Medicina, Botucatu Street, 740 - Vila Clementino, São Paulo, SP, Brazil; Laboratory of Molecular and Experimental Pathology, Universidade Federal de São Paulo, Escola Paulista de Medicina, Pedro de Toledo Street, 781, 5º floor - Vila Clementino, São Paulo, SP, Brazil. Electronic address: debsalles@gmail.com.
⁴ Laboratory of Molecular and Experimental Pathology, Universidade Federal de São Paulo, Escola Paulista de Medicina, Pedro de Toledo Street, 781, 5º floor - Vila Clementino, São Paulo, SP, Brazil; Graduate student of Escola Paulista de Enfermagem, Universidade Federal de São Paulo, Napoleão de Barros Street, 754 - Vila Clementino, São Paulo, SP, Brazil. Electronic address: cslourenco@unifesp.br.
⁵ Laboratory of Molecular and Experimental Pathology, Universidade Federal de São Paulo, Escola Paulista de Medicina, Pedro de Toledo Street, 781, 5º floor - Vila Clementino, São Paulo, SP, Brazil. Electronic address: daribeiro@unifesp.br.
⁶ Department of Obstetrics, Universidade Federal de São Paulo, Escola Paulista de Medicina, Napoleão de Barros Street, 875 - Vila Clementino, São Paulo, SP, Brazil. Electronic address: sueysun@gmail.com.
⁷ Department of Pathology, Universidade Federal de São Paulo, Escola Paulista de Medicina, Botucatu Street, 740 - Vila Clementino, São Paulo, SP, Brazil; Laboratory of Molecular and Experimental Pathology, Universidade Federal de São Paulo, Escola Paulista de Medicina, Pedro de Toledo Street, 781, 5º floor - Vila Clementino, São Paulo, SP, Brazil. Electronic address: mms.ishigai@gmail.com.
⁸ Department of Pathology, Universidade Federal de São Paulo, Escola Paulista de Medicina, Botucatu Street, 740 - Vila Clementino, São Paulo, SP, Brazil; Laboratory of Molecular and Experimental Pathology, Universidade Federal de São Paulo, Escola Paulista de Medicina, Pedro de Toledo Street, 781, 5º floor - Vila Clementino, São Paulo, SP, Brazil. Electronic address: edna.iwamura@unifesp.br.
⁹ Department of Pathology, Universidade Federal de São Paulo, Escola Paulista de Medicina, Botucatu Street, 740 - Vila Clementino, São Paulo, SP, Brazil. Electronic address: mtsalves@unifesp.br.
¹⁰ Department of Pathology, Universidade Federal de São Paulo, Escola Paulista de Medicina, Botucatu Street, 740 - Vila Clementino, São Paulo, SP, Brazil; Laboratory of Molecular and Experimental Pathology, Universidade Federal de São Paulo, Escola Paulista de Medicina, Pedro de Toledo Street, 781, 5º floor - Vila Clementino, São Paulo, SP, Brazil. Electronic address: andreamoraesmalinverni@gmail.com.

PMID: 35961058
DOI: 10.1016/j.prp.2022.154041

Abstract

Hydatidiform mole is an abnormal pregnancy in which two copies of paternal genetic material are present. Molar gestation is divided into complete and partial hydatidiform moles. Clinical, morphological, and cytogenetic characteristics are usually sufficient to distinguish them, but and the rare cases that are necessary to know the paternal origin to establish the diagnosis and segment? Mutations in the Gene for Factor V Leiden and G20210A prothrombin polymorphism in women with recurrent spontaneous abortion: a retrospective study in a Brazilian population.

Keywords: Abnormal pregnancy; Diagnostic Techniques; Hydatidiform mole; Molecular genotyping.

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Conflict of interest statement

Declaration of Conflicting Interest The authors declared no potential conflicts of interest concerning the research, authorship, and/or publication of this article.

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Complementary tool in diagnosis of hydatidiform mole: Review

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Complementary tool in diagnosis of hydatidiform mole: Review

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