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Comment
. 2022 Aug 12;7(1):279.
doi: 10.1038/s41392-022-01089-6.

Engineered virus-like particles: paving the way for effective somatic genome editing

Chenya Zhuo  1 , Yu Tao  2 , Mingqiang Li  3   4
Affiliations
Comment

Engineered virus-like particles: paving the way for effective somatic genome editing

Chenya Zhuo et al. Signal Transduct Target Ther. .
No abstract available

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Conflict of interest statement

The authors declare no competing interests.

Figures

Fig. 1
Fig. 1
Illustration of structure and engineering approaches of virus-like particles (eVLPs) and the potential applications of v4 BE-eVLPs. a The engineering strategies to improve BE-eVLPs for somatic genome editing. Four generations of BE-eVLPs were produced in the study by optimizing cleavable linker, gag–BE fusion localization, and gag–BE:gag-pro-pol stoichiometry. b The production of v4 BE-eVLPs and its potential in vivo applications. Adapted with permission. Copyright 2022, Elsevier
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References

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