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Comment
. 2022 Aug 12;3(8):523-525.
doi: 10.1016/j.medj.2022.07.005.

Nocturnal circulating tumor cells: The ultimate selective filter in cancer progression?

Frédéric Thomas  1 , Antoine M Dujon  2 , Beata Ujvari  3 , Catherine Alix-Panabières  4
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Free article
Comment

Nocturnal circulating tumor cells: The ultimate selective filter in cancer progression?

Frédéric Thomas et al. Med. .
Free article

Abstract

The survival duration of circulating tumor cells (CTCs) in the vasculature is a critical parameter in the establishment of the metastatic cascade. Diamantopoulou and colleagues demonstrate that the metastatic capacity of CTCs is strongly influenced by circadian rhythms, suggesting a rationale for the time-controlled interrogation and treatment of metastatic cancers.

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Conflict of interest statement

Declaration of interests C.A.-P. has received honoraria from Menarini and patent applications related to CTC technologies.

Comment on

  • The metastatic spread of breast cancer accelerates during sleep.
    Diamantopoulou Z, Castro-Giner F, Schwab FD, Foerster C, Saini M, Budinjas S, Strittmatter K, Krol I, Seifert B, Heinzelmann-Schwarz V, Kurzeder C, Rochlitz C, Vetter M, Weber WP, Aceto N. Diamantopoulou Z, et al. Nature. 2022 Jul;607(7917):156-162. doi: 10.1038/s41586-022-04875-y. Epub 2022 Jun 22. Nature. 2022. PMID: 35732738

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