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Comment
. 2022 Nov;102(5):951-953.
doi: 10.1016/j.kint.2022.07.016. Epub 2022 Aug 10.

How does diabetes cause susceptibility to COVID-19 in the kidney: new clues provided by organoids

Yun Xia  1 , P Toby Coates  2 , Masaomi Nangaku  3
Affiliations
Comment

How does diabetes cause susceptibility to COVID-19 in the kidney: new clues provided by organoids

Yun Xia et al. Kidney Int. 2022 Nov.
No abstract available

Keywords: ACE2; SARS-CoV-2; diabetes mellitus; diabetic kidney disease; fibrosis; kidney organoid.

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Figures

Figure 1
Figure 1
Experimental scheme of the study. Human pluripotent stem cells (hPSCs) were differentiated into kidney organoids. From day 16 to day 23, 5 mM glucose treatment and oscillatory high-glucose treatment were employed to generate control and diabetic kidney organoids, respectively. On day 23, both control and diabetic kidney organoids were infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) for 24 hours. ACE2, angiotensin-converting enzyme 2.
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References

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