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Review
. 2022 Sep;51(3):483-509.
doi: 10.1016/j.ecl.2022.02.005. Epub 2022 Jul 4.

Assessment of Cardiovascular Disease Risk: A 2022 Update

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Review

Assessment of Cardiovascular Disease Risk: A 2022 Update

Earl Goldsborough 3rd et al. Endocrinol Metab Clin North Am. 2022 Sep.

Abstract

Assessment of atherosclerotic cardiovascular disease (ASCVD) risk is the cornerstone of primary ASCVD prevention, enabling targeted use of the most aggressive therapies in those most likely to benefit, while guiding a conservative approach in those who are low risk. ASCVD risk assessment begins with the use of a traditional 10-year risk calculator, with further refinement through the consideration of risk-enhancing factors (particularly lipoprotein(a)) and subclinical atherosclerosis testing (particularly coronary artery calcium (CAC) testing). In this review, we summarize the current field of ASCVD risk assessment in primary prevention and highlight new guidelines from the Endocrine Society.

Keywords: Atherosclerosis; Cardiovascular disease; Cardiovascular risk; Coronary artery calcium; Family history; Lipoprotein(a); Primary prevention; Risk assessment.

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Conflict of interest statement

Disclosure E. Goldsborough has no financial disclosures or competing interests to report. N. Osuji has no financial disclosures or competing interests to report.

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