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. 2022 Jul;8(4):897-900.
doi: 10.1016/j.euf.2022.08.001. Epub 2022 Aug 10.

Trials in the Key of G: Building Level 1 Evidence on the Real-world Effectiveness of Prostate Biomarkers

Linda A Okoth  1 , Anna C Harris  1 , Udit Singhal  2 , Michael L Cher  3 , Daniel E Spratt  4 , Todd M Morgan  5
Affiliations

Trials in the Key of G: Building Level 1 Evidence on the Real-world Effectiveness of Prostate Biomarkers

Linda A Okoth et al. Eur Urol Focus. 2022 Jul.

Abstract

A number of genomic classifiers are available to aid in shared decision-making for men with localized prostate cancer; however, there is no high-level evidence assessing their clinical utility. The two randomized controlled trials in this report prospectively evaluate the use of gene expression classifier testing at the time of cancer diagnosis and after surgical treatment.

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Figures

Fig. 1:
Fig. 1:
G-MINOR Trial Schema
Fig. 2:
Fig. 2:
G-MAJOR Trial Schema
See this image and copyright information in PMC

References

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