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Case Reports
. 2022 Apr-Jun;26(2):259-262.
doi: 10.4103/jomfp.jomfp_444_21. Epub 2022 Jun 28.

Intraoral malignant glomus tumor

Satheesh Chandran  1 , Arun Elangovan  2 , Saranya Vijayakumar  3 , K Sai Sarath Kumar  4
Affiliations
Case Reports

Intraoral malignant glomus tumor

Satheesh Chandran et al. J Oral Maxillofac Pathol. 2022 Apr-Jun.

Abstract

Glomus tumors are uncommon, benign solitary tumors derived from the glomus apparatus. We report here a case of a malignant glomus tumor in an 8-year-old child presenting as a multilocular ill-defined radiolucency of the mandible. The lesion microscopically showed sheets of round basophilic cells with high nuclear-cytoplasmic ratio, indistinct cell boundaries, nuclear hyperchromatism and nuclear pleomorphism. Immunohistochemically, the tumor was positive for vimentin and smooth muscle actin.

Keywords: Child; glomus tumor; malignant; mandible; oral; pedodontia; vimentin.

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
Intraoral growth in the alveolar region body of the mandible
Figure 2
Figure 2
Orthopantomogram revealed ai ill-defined multilocular radiolucency
Figure 3
Figure 3
Gross specimen
Figure 4
Figure 4
(a) Sheets of round cells with basophilic cytoplasam, high nuclear-cytoplasmic ratio and indistinct cell boundaries (H and E, ×40). (b) The presence of mitotic figures (H and E, ×40). (c) The tumor cells show diffuse positivity for vimentin (immunohistochemistry, ×10). (d) The tumor cells show focal positivity for smooth muscle actin (immunohistochemistry, ×10)
See this image and copyright information in PMC

References

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