A Background Search on the Potential Role of Scutellaria and Its Essential Oils
- PMID: 35968239
- PMCID: PMC9365597
- DOI: 10.1155/2022/7265445
A Background Search on the Potential Role of Scutellaria and Its Essential Oils
Abstract
Scutellaria (Lamiaceae), which contains over 350 species, usually known as skullcaps, is found throughout Europe, the United States, and East Asia. In traditional Chinese medicine, several species are used to wipe out heat-evil and remove surface ills (TCM). The current study examines the ethnopharmacology, biological activity, and chemical substances associated with Scutellaria species. More than 295 chemicals, including flavonoids and diterpenes, have been identified. Scutellaria and its active principles have been shown in studies to have a wide range of pharmacological activities, including antioxidant, antimicrobial, antifeedant, phytotoxic, acaricidal toxicity, antibacterial, anti-inflammatory, and antianalgesic activities. Currently, effective monomeric compounds or active components from Scutellaria have been evaluated for pharmacological action in vivo and in vitro. More data facilitates applications and exploitation of novel medication development.
Copyright © 2022 Mehrukh Zehravi et al.
Conflict of interest statement
The authors declare no conflict of interest.
Figures
Similar articles
-
The genus Scutellaria an ethnopharmacological and phytochemical review.J Ethnopharmacol. 2010 Mar 24;128(2):279-313. doi: 10.1016/j.jep.2010.01.006. Epub 2010 Jan 11. J Ethnopharmacol. 2010. PMID: 20064593 Review.
-
Traditional uses, ten-years research progress on phytochemistry and pharmacology, and clinical studies of the genus Scutellaria.J Ethnopharmacol. 2021 Jan 30;265:113198. doi: 10.1016/j.jep.2020.113198. Epub 2020 Jul 30. J Ethnopharmacol. 2021. PMID: 32739568
-
Diterpenes of Scutellaria spp.: Phytochemistry and pharmacology.Phytochemistry. 2022 Sep;201:113285. doi: 10.1016/j.phytochem.2022.113285. Epub 2022 Jun 18. Phytochemistry. 2022. PMID: 35728674 Review.
-
A review of the ethnopharmacology, phytochemistry, pharmacology, and quality control of Scutellaria barbata D. Don.J Ethnopharmacol. 2020 May 23;254:112260. doi: 10.1016/j.jep.2019.112260. Epub 2019 Sep 29. J Ethnopharmacol. 2020. PMID: 31577937
-
Composition of the essential oils of three Uzbek Scutellaria species (Lamiaceae) and their antioxidant activities.Nat Prod Res. 2017 May;31(10):1172-1176. doi: 10.1080/14786419.2016.1222383. Epub 2016 Aug 22. Nat Prod Res. 2017. PMID: 27545726
Cited by
-
Composition and Antioxidative and Antibacterial Activities of the Essential Oil from Farfugium japonicum.Molecules. 2023 Mar 19;28(6):2774. doi: 10.3390/molecules28062774. Molecules. 2023. PMID: 36985745 Free PMC article.
-
Clinically proven natural products against breast cancer, with mechanistic insights.Oncol Res. 2025 Jun 26;33(7):1611-1632. doi: 10.32604/or.2025.062778. eCollection 2025. Oncol Res. 2025. PMID: 40612872 Free PMC article. Review.
References
-
- Bruno M., Piozzi F., Maggio A. M., Simmonds M. S. Antifeedant activity of neoclerodane diterpenoids from two Sicilian species of Scutellaria. Biochemical Systematics and Ecology . 2002;30(8):793–799. doi: 10.1016/S0305-1978(01)00143-0. - DOI
-
- Cole I. B., Saxena P. K., Murch S. J. Medicinal biotechnology in the genus Scutellaria. Vitro Cellular & Developmental Biology-Plant . 2007;43(4):318–327. doi: 10.1007/s11627-007-9055-4. - DOI
-
- Scheen A. C., Albert V. A. Molecular phylogenetics of the Leucas group (Lamioideae; Lamiaceae) Systematic Botany . 2009;34(1):173–181.
-
- Minareci E., Pekönür S. An important Euroasian genus: Scutellaria L. International Journal of Secondary Metabolite . 2017;4(1):35–46.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources