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Comment
. 2022 Sep;20(9):2161-2163.
doi: 10.1111/jth.15790.

"Unconventional CD147-dependent platelet activation elicited by SARS-CoV-2 in COVID-19": Reply

Norma Maugeri  1   2 , Angelo A Manfredi  1   2
Affiliations
Comment

"Unconventional CD147-dependent platelet activation elicited by SARS-CoV-2 in COVID-19": Reply

Norma Maugeri et al. J Thromb Haemost. 2022 Sep.
No abstract available

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Figures

FIGURE 1
FIGURE 1
HMGB1+ plt‐EVs concentration is associated with COVID‐19 severity and predicts clinical outcomes. The concentration of total EV retrieved in the plasma of patients with COVID 19 are higher respect to healthy controls (A) and is not associated with the severity of disease (B). The concentration of total EV do not correlates with concentration of C‐reactive protein (CRP; C), of D‐dimer (D), of lactate dehydrogenase (LDH, E) neither is higher in patients who will develop acute respiratory distress syndrome (ARDS, F). On the contrary, the concentration of HMGB1+ plt‐EV is significantly associated to disease severity and predict clinical outcomes (G). Symbols depict individual observations in each subject. ****p < .0001; ***p < .001.
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References

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