Pharmacogenomics guided dosing for fluoropyrimidine and irinotecan chemotherapies for patients with cancer (PACIFIC-PGx): study protocol of a multicentre clinical trial

Sarah Glewis^{1

2}, Marliese Alexander^{1

2}, Senthil Lingaratnam¹, Benjamin Lee¹, Ian Campbell^{2

3}, Mei Krishnasamy^{2

4

5}, Maarten IJzerman^{2

6

7}, Mussab Fagery⁶, Sam Harris⁸, Chloe Georgiou⁸, Craig Underhill^{5

9

10}, Mark Warren⁸, Robert Campbell⁸, Jennifer Martin¹¹, Jeanne Tie^{2

12

13}, Michael Michael^{2

12}

Affiliations

¹ Department of Pharmacy, Peter MacCallum Cancer Centre, Melbourne, Australia.
² Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Australia.
³ Cancer Genetics Laboratory, Peter MacCallum Cancer Centre, Melbourne, Australia.
⁴ Academic Nursing Unit, Peter MacCallum Cancer Centre, Melbourne, Australia.
⁵ VCCC Alliance, Parkville, Australia.
⁶ Cancer Research, University of Melbourne, Parkville, Australia.
⁷ Melbourne School of Population and Global Health, Centre for Health Policy, University of Melbourne, Parkville, Australia.
⁸ Department of Medical Oncology, Bendigo Health, Bendigo, Australia.
⁹ Border Medical Oncology Research Unit, Albury Wodonga Regional Cancer Centre, East Albury, Australia.
¹⁰ UNSW Rural Medical School, East Albury, Australia.
¹¹ School of Medicine and Public Health, University of Newcastle, Callaghan, Australia.
¹² Department of Medical Oncology, Peter MacCallum Cancer Centre, Melbourne, Australia.
¹³ Personalised Oncology Division, Walter and Eliza Hall Institute of Medical Research, Parkville, Australia.

Sarah Glewis et al. Acta Oncol. 2022 Sep.

. 2022 Sep;61(9):1136-1139.

doi: 10.1080/0284186X.2022.2109423. Epub 2022 Aug 16.

¹ Department of Pharmacy, Peter MacCallum Cancer Centre, Melbourne, Australia.
² Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Australia.
³ Cancer Genetics Laboratory, Peter MacCallum Cancer Centre, Melbourne, Australia.
⁴ Academic Nursing Unit, Peter MacCallum Cancer Centre, Melbourne, Australia.
⁵ VCCC Alliance, Parkville, Australia.
⁶ Cancer Research, University of Melbourne, Parkville, Australia.
⁷ Melbourne School of Population and Global Health, Centre for Health Policy, University of Melbourne, Parkville, Australia.
⁸ Department of Medical Oncology, Bendigo Health, Bendigo, Australia.
⁹ Border Medical Oncology Research Unit, Albury Wodonga Regional Cancer Centre, East Albury, Australia.
¹⁰ UNSW Rural Medical School, East Albury, Australia.
¹¹ School of Medicine and Public Health, University of Newcastle, Callaghan, Australia.
¹² Department of Medical Oncology, Peter MacCallum Cancer Centre, Melbourne, Australia.
¹³ Personalised Oncology Division, Walter and Eliza Hall Institute of Medical Research, Parkville, Australia.

No abstract available

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