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Editorial
. 2022 Aug 1;9(8):141-144.
doi: 10.15698/mic2022.08.782.

The rise of Candida auris: from unique traits to co-infection potential

Nadine B Egger  1 , Katharina Kainz  1 , Adina Schulze  1 , Maria A Bauer  1 , Frank Madeo  1   2   3 , Didac Carmona-Gutierrez  1
Affiliations
Editorial

The rise of Candida auris: from unique traits to co-infection potential

Nadine B Egger et al. Microb Cell. .

Abstract

Candida auris is a multidrug resistant (MDR) fungal pathogen with a crude mortality rate of 30-60%. First identified in 2009, C. auris has been rapidly emerging to become a global risk in clinical settings and was declared an urgent health threat by the Centers for Disease Control and Prevention (CDC). A concerted global action is thus needed to successfully tackle the challenges created by this emerging fungal pathogen. In this brief article, we underline the importance of unique virulence traits,including its easy transformation, its persistence outside the host and its resilience against multiple cellular stresses, as well as of environmental factors that have mainly contributed to the rise of this superbug.

Keywords: COVID-19; Candida auris; SARS-CoV2; biofilm; candidemia; co-infection; fungal infections; global warming; nosocomial infection; pandemic; resistance; yeast.

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Conflict of interest statement

Conflict of Interest: The authors declare no conflict of interest.

References

    1. World Health Organization. The World Health Report 2007. 2007. Available at: https://www.who.int/publications/i/item/9789241563444 [Accessed: 29.06.2022]
    1. Du H, Bing J, Hu T, Ennis CL, Nobile CJ, Huang G. Candida auris: Epidemiology, biology, antifungal resistance, and virulence. PLoS Pathog. 2020;16(10):e1008921. doi: 10.1371/journal.ppat.1008921. - DOI - PMC - PubMed
    1. Ahmad S, Alfouzan W. Candida auris: Epidemiology, Diagnosis, Pathogenesis, Antifungal Susceptibility, and Infection Control Measures to Combat the Spread of Infections in Healthcare Facilities. Microorganisms. 2021;9(4):807. doi: 10.3390/microorganisms9040807. - DOI - PMC - PubMed
    1. Černáková L, Roudbary M, Brás S, Tafaj S, Rodrigues CF. Candida auris: A Quick Review on Identification, Current Treatments, and Challenges. Int J Mol Sci. 2021;22(9):4470. doi: 10.3390/ijms22094470. - DOI - PMC - PubMed
    1. Chow NA, de Groot T, Badali H, Abastabar M, Chiller TM, Meis JF. Potential Fifth Clade of Candida auris, Iran, 2018. Emerg Infect Dis. 2019;25(9):1780–1781. doi: 10.3201/eid2509.190686. - DOI - PMC - PubMed

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