Potential conflicts of interest. L. M. M. reports a contract from ViiV; consulting fees from the World Health Organization and UNICEF; and payment or honoraria from Virology Education for Webinar on 2021 Pediatric HIV Workshop and from the Canadian Association for HIV Research. U. M. R. reports honoraria paid to author for participation as a panel member on the US Food and Drug Administration (FDA) Antimicrobial Drug Advisory Committee ad hoc, serving as a National Advisory Board member for Patient-Centered Outcomes Research Institute (PCORI), serving as a data and safety monitoring board member for the Umbilical Cord Milking in Non-Vigorous Infants Trial funded by the Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, and as an advisory committee member for the Support Models for Addiction Related Treatment Trial of Opioid Use Disorder in Pregnant Women Study funded by PCORI. G. K. S. reports unpaid participation as a US federal government member of the FDA Antimicrobial Drug Advisory Committee. A.C. reports grants or contracts from MSD (research grant) and payment or honoraria for lectures, presentations, speakers bureaus, manuscript writing, or educational events from Gilead, ViiV Healthcare, and MSD (yearly; unrestricted educational grants to institution). All other authors report no potential conflicts. All authors have submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Conflicts that the editors consider relevant to the content of the manuscript have been disclosed.