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Review
. 2022 Sep 1;135(3):545-557.
doi: 10.1213/ANE.0000000000006149. Epub 2022 Aug 17.

Transfusion Strategies for Hemostatic Blood Products in Critically Ill Children: A Narrative Review and Update on Expert Consensus Guidelines

Stacey L Valentine  1 , Jill M Cholette  2 , Susan M Goobie  3
Affiliations
Review

Transfusion Strategies for Hemostatic Blood Products in Critically Ill Children: A Narrative Review and Update on Expert Consensus Guidelines

Stacey L Valentine et al. Anesth Analg. .

Abstract

Critically ill children commonly receive coagulant products (plasma and/or platelet transfusions) to prevent or treat hemorrhage or correct coagulopathy. Unique aspects of pediatric developmental physiology, and the complex pathophysiology of critical illness must be considered and balanced against known transfusion risks. Transfusion practices vary greatly within and across institutions, and high-quality evidence is needed to support transfusion decision-making. We present recent recommendations and expert consensus statements to direct clinicians in the decision to transfuse or not to transfuse hemostatic blood products, including plasma, platelets, cryoprecipitate, and recombinant products to critically ill children.

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Conflict of interest statement

The authors declare no conflicts of interest.

References

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