Biogenesis of post-translationally modified peptide signals for plant reproductive development

Abstract

Post-translationally modified peptides (PMPs) are important regulators of plant growth and development. They are derived from larger inactive precursors by post-translational modification (PTM) and proteolytic processing to result in the bioactive peptide signals. We discuss how and why these modifications contribute to the bioactivity of inflorescence deficient in abscission (IDA), phytosulfokine (PSK), and peptides of the Casparian strip integrity factor (CIF) family, as signaling molecules during reproductive development. The emerging picture suggests that PTMs evolved to increase the specificity of interaction of PMPs with cognate receptors and of PMP precursors with processing proteases. Cleavage sites in PMP precursors are recognized by subtilases (SBTs) in a highly specific manner. SBT-mediated processing results in the activation of PMP signals regulating stress-induced flower drop, the formation of the embryonic cuticle, and pollen development.

Keywords: Casparian strip integrity factor (CIF); Inflorescence deficient in abscission (IDA); Peptide hormone; Phytosulfokine (PSK); Precursor processing; Subtilase (SBT); Twisted seed (TWS); Tyrosylprotein sulfotransferase (TPST).