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. 2022 Aug 17;22(1):897.
doi: 10.1186/s12885-022-09921-6.

Quality of life and its influencing factors among breast cancer patients at Tikur Anbessa specialised hospital, Addis Ababa, Ethiopia

Mikiyas Amare Getu  1   2   3 , Changying Chen  4 , Panpan Wang  5 , Eva Johanna Kantelhardt  6   7 , Adamu Addissie  6   8
Affiliations

Quality of life and its influencing factors among breast cancer patients at Tikur Anbessa specialised hospital, Addis Ababa, Ethiopia

Mikiyas Amare Getu et al. BMC Cancer. .

Abstract

Background: Quality of life (QoL) has become an important measure for evaluating cancer patients' treatment and prognosis. Breast cancer patients are at an increased risk of experiencing poor QoL during active treatment of cancer. This study aimed to assess QoL and it's influencing factors among breast cancer patients using the newly updated breast cancer specific tool of the European Organisation for Research and Treatment of Cancer EORTC Breast Cancer Specific Quality of Life Questionnaire QLQ-BR45.

Methods: An institutional based crossectional study was conducted with 248 breast cancer patients at Tikur Anbessa Specialized Hospital (TASH). Descriptive statistics, one-way analysis of variance (ANOVA), and linear regression were used to describe and analyze the data.

Results: The participant's Global health status/QoL mean score was 65.6. Among the functional scales, future perspective scored the lowest (57.1, SD ± 37.3). The highest mean score on the symptom scales/items were financial difficulties (50, SD ± 38.6), followed by appetite loss (37.4, SD ± 36.4) and fatigue (34.3, SD ± 27.1) while the lowest symptom score was diarrhoea (6.4 ± 18.4). EORTC QLQ-BR45, future perspective (mean = 57.1, SD ± 37.3) and upset by hair loss (41.8, SD ± 34.6) were the most affected functioning and symptoms scales respectively. An increased stage of tumor was associated with more pain (P = 0.041), appetite loss (P = 0.042), and arm symptoms (P = 0.003). Patients who had no comorbidity had better physical (P < 0.001), cognitive (P = 0.013), and social (P = 0.009) function.

Conclusion: These specific functional scales and symptoms should be assessed individually to address unmet needs. Clinicians could design psychosocial interventions to improve these function and to reduce symptoms.

Keywords: Breast cancer; EORTC QLQ-BR45; EORTC QLQ-C30; Ethiopia; Quality of life.

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Conflict of interest statement

The authors have no relevant financial or non-financial interests to disclose.

References

    1. Sung H, et al. Global Cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2021;71(3):209–249. doi: 10.3322/caac.21660. - DOI - PubMed
    1. International Agency for Research on Cancer: World Health Organization, “The Global Cancer Observatory:Ethiopia,” 2021. https://gco.iarc.fr/today/data/factsheets/populations/231-ethiopia-fact-....
    1. World Health Organization, “WHO | WHOQOL: Measuring Quality of Life,” 2020. https://www.who.int/healthinfo/survey/whoqol-qualityoflife/en/ (accessed Apr 22, 2020).
    1. Montazeri A, Gillis CR, McEwen J. Measuring quality of life in oncology: is it worthwhile? II. Experiences from the treatment of cancer. Eur J Cancer Care (Engl) 1996;5(3):168–175. doi: 10.1111/j.1365-2354.1996.tb00229.x. - DOI - PubMed
    1. Montazeri A, Milroy R, Hole D, McEwen J, Gillis CR. How quality of life data contribute to our understanding of cancer patients’ experiences? A study of patients with lung cancer. Qual Life Res. 2003;12(2):157–166. doi: 10.1023/A:1022232624891. - DOI - PubMed