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. 2022:7:e220003.
doi: 10.20900/jpbs.20220003. Epub 2022 Jun 27.

Cerebellar Structure and Function in Autism Spectrum Disorder

Bess F Bloomer  1 , Jaime J Morales  1   2 , Amanda R Bolbecker  1 , Dae-Jin Kim  1 , William P Hetrick  1   2   3
Affiliations

Cerebellar Structure and Function in Autism Spectrum Disorder

Bess F Bloomer et al. J Psychiatr Brain Sci. 2022.

Abstract

Autism spectrum disorder (ASD) is a heterogeneous neurodevelopmental condition characterized by early-onset repetitive behaviors, restricted interests, sensory and motor difficulties, and impaired social interactions. Converging evidence from neuroimaging, lesion and postmortem studies, and rodent models suggests cerebellar involvement in ASD and points to promising targets for therapeutic interventions for the disorder. This review elucidates understanding of cerebellar mechanisms in ASD by integrating and contextualizing recent structural and functional cerebellar research.

Keywords: autism spectrum disorder; cerebellum; cognition; development.

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Conflict of interest statement

CONFLICTS OF INTEREST The authors declare no conflicts of interest with respect to the authorship or the publication of this article.

Figures

Figure 1.
Figure 1.
A visual summary of ASD-specific cerebellar differences.
See this image and copyright information in PMC

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