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. 2022 Aug 1:9:970787.
doi: 10.3389/fcvm.2022.970787. eCollection 2022.

Prevalence, awareness, treatment, and control rates of hypertension in patients hospitalized with atrial fibrillation in China: Findings from the CCC-AF project

Zhaoqing Sun  1 , Yongchen Hao  1 , Jun Liu  1 , Na Yang  1 , Yue Qi  1 , Danqing Hu  1 , Yiqian Yang  1 , Haimei Wang  1 , Dong Zhao  1 , Caihua Sang  2 , Jing Liu  1
Affiliations

Prevalence, awareness, treatment, and control rates of hypertension in patients hospitalized with atrial fibrillation in China: Findings from the CCC-AF project

Zhaoqing Sun et al. Front Cardiovasc Med. .

Abstract

Background: The status of hypertension in patients with atrial fibrillation (AF) remains unknown in China.

Methods: This study used data from patients hospitalized with AF recruited by the Improving Care for Cardiovascular Disease in China-AF (CCC-AF) project from 236 hospitals enrolled by geographic-economic level in China from 2015 to 2019. The prevalence, awareness, treatment, and control rates of hypertension in patients hospitalized with AF were estimated. Multivariable logistic regression was used to analyze the factors associated with uncontrolled hypertension.

Results: Among 60,390 patients hospitalized with AF, the prevalence of hypertension according to the 2018 Chinese hypertension guidelines was 66.1%. The awareness, treatment, and control rates of hypertension were 80.3, 55.8, and 39.9%, respectively. Among patients treated for hypertension, the treatment control rate was 46.2%. These rates varied according to patient clinical characteristics and geographic regions. The young (18-44 and 45-54 years old), rural insurance, alcohol drinking, history of heart failure, valvular AF, first diagnosed AF, and permanent AF, were associated with uncontrolled hypertension. Under the 2017 American College of Cardiology/American Heart Association (ACC/AHA) hypertension guidelines, the prevalence of hypertension was 79.3%, and the control and treatment control rates dropped to 16.7 and 21.2%, respectively.

Conclusion: Hypertension is common in patients hospitalized with AF in China. Although most patients were aware of their hypertensive status, the treatment and control rates of hypertension were still low. The management of hypertension in patients with AF needs to be further improved.

Keywords: atrial fibrillation; awareness; control; hypertension; prevalence; treatment.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
Prevalence of hypertension in patients hospitalized with atrial fibrillation (AF) in different age groups. (A) According to the 2018 Chinese hypertension guidelines; (B) according to the 2017 American College of Cardiology/American Heart Association (ACC/AHA) hypertension guidelines.
Figure 2
Figure 2
Prevalence of hypertension in patients hospitalized with atrial fibrillation (AF) in seven regions of China. (A) According to the 2018 Chinese hypertension guidelines; (B) according to the 2017 American College of Cardiology/American Heart Association (ACC/AHA) hypertension guidelines. The prevalence of hypertension is represented in red.
Figure 3
Figure 3
Changes in the status of hypertension in patients hospitalized with atrial fibrillation (AF) in China from 2015 to 2019. (A) According to the 2018 Chinese hypertension guidelines; (B) according to the 2017 American College of Cardiology/American Heart Association (ACC/AHA) hypertension guidelines.
Figure 4
Figure 4
Factors associated with uncontrolled hypertension in patients hospitalized with atrial fibrillation and hypertension based on the 2018 Chinese hypertension guidelines. OR, odds ratio; CI, confidence interval; CHD, coronary heart disease; AF, atrial fibrillation. Adjusted variables: age, sex, medical insurance, smoking, alcohol drinking, CHD, heart failure, cerebrovascular disease, diabetes mellitus, previous bleeding, antihypertensive drugs, etiological diagnosis of AF, and types of AF.
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