Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2022 Aug 1:10:893431.
doi: 10.3389/fped.2022.893431. eCollection 2022.

Thermal servo-controlled systems in the management of VLBW infants at birth: A systematic review

Affiliations
Review

Thermal servo-controlled systems in the management of VLBW infants at birth: A systematic review

Orietta Ercolino et al. Front Pediatr. .

Abstract

Background: Thermal management of the newborn at birth remains an actual challenge. This systematic review aimed to summarize current evidence on the use of thermal servo-controlled systems during stabilization of preterm and VLBW infants immediately at birth.

Methods: A comprehensive search was conducted including MEDLINE/Pubmed, EMBASE, SCOPUS, clinicaltrials.gov, and the Cochrane Database through December 2021. PRISMA guidelines were followed. Risk of bias was appraised using Cochrane RoB2 and Risk Of Bias In Non-Randomized Studies of Interventions (ROBIN-I) tools, and certainty of evidence using GRADE framework.

Results: One randomized controlled trial and one observational study were included. Some aspects precluded the feasibility of a meaningful meta-analysis; hence, a qualitative review was conducted. Risk of bias was low in the trial and serious in the observational study. In the trial, the servo-controlled system did not affect normothermia (36.5-37.5°C) but was associated with increased mild hypothermia (from 22.2 to 32.9%). In the observational study, normothermia (36-38°C) increased after the introduction of the servo-controlled system and the extension to larger VLBW infants.

Conclusion: Overall, this review found very limited information on the use of thermal servo-controlled systems during stabilization of preterm and VLBW infants immediately at birth. Further research is needed to investigate the opportunity of including such approach in the neonatal thermal management in delivery room.

Registration: PROSPERO (CRD42022309323).

Keywords: delivery room; preterm infants; review—systematic; servo-controlled system; temperature.

PubMed Disclaimer

Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
PRISMA flow diagram.

References

    1. Wyckoff MH, Wyllie J, Aziz K, de Almeida MF, Fabres J, Fawke J, et al. . Neonatal life support: 2020 international consensus on cardiopulmonary resuscitation and emergency cardiovascular care science with treatment recommendations. Circulation. (2020) 142(16_Suppl_1):S185–221. 10.1542/peds.2020-038505C - DOI - PubMed
    1. Soraisham AS, Lodha AK, Singhal N, Aziz K, Yang J, Lee SK, et al. . Neonatal outcomes following extensive cardiopulmonary resuscitation in the delivery room for infants born at less than 33 weeks gestational age. Resuscitation. (2014) 85:238. 10.1016/j.resuscitation.2013.10.016 - DOI - PubMed
    1. Madar J, Roehr CC, Ainsworth S, Ersdal H, Morley C, Rüdiger M, et al. . European resuscitation council guidelines 2021: newborn resuscitation and support of transition of infants at birth. Resuscitation. (2021) 161:291–326. 10.1016/j.resuscitation.2021.02.014 - DOI - PubMed
    1. Wilson E, Maier RF, Norman M, Misselwitz B, Howell EA, Zeitlin J, et al. . Admission hypothermia in very preterm infants and neonatal mortality and morbidity. J Pediatr. (2016) 175:61. 10.1016/j.jpeds.2016.04.016 - DOI - PubMed
    1. de Almeida MF, Guinsburg R, Sancho GA, Rosa IRM, Lamy ZC, Martinez FE, et al. . Hypothermia and early neonatal mortality in preterm infants. J Pediatr. (2014) 164:271. 10.1016/j.jpeds.2013.09.049 - DOI - PubMed

LinkOut - more resources