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. 2022 Aug 1;5(8):e2225964.
doi: 10.1001/jamanetworkopen.2022.25964.

Association of Insurance Coverage With Adoption of Sleeve Gastrectomy vs Gastric Bypass for Patients Undergoing Bariatric Surgery

Ryan Howard  1   2 , Edward C Norton  3   4 , Jie Yang  2 , Jyothi Thumma  2 , David E Arterburn  5 , Andrew Ryan  2   3   6 , Dana Telem  1   2   7 , Justin B Dimick  1   2   7
Affiliations

Association of Insurance Coverage With Adoption of Sleeve Gastrectomy vs Gastric Bypass for Patients Undergoing Bariatric Surgery

Ryan Howard et al. JAMA Netw Open. .

Abstract

Importance: Instrumental variables can control for selection bias in observational research. However, valid instruments are challenging to identify.

Objective: To evaluate regional variation in sleeve gastrectomy following insurance coverage implementation as an instrumental variable in comparative effectiveness research.

Design, setting, and participants: This serial cross-sectional study included adult patients in a national Medicare claims database who underwent sleeve gastrectomy or Roux-en-Y gastric bypass from 2012 to 2017. Data analysis was performed from January to June 2021.

Exposures: Laparoscopic sleeve gastrectomy and Roux-en-Y gastric bypass.

Main outcomes and measures: The association of the instrumental variable with treatment (ie, undergoing sleeve gastrectomy), as well as mortality, complications, emergency department visits, hospitalization, reinterventions, and surgical revision.

Results: A total of 76 077 patients underwent bariatric surgery, of whom 44 367 underwent sleeve gastrectomy (mean [SD] age, 56.9 [11.9] years; 32 559 [73.5%] women) and 31 710 underwent gastric bypass (mean (SD) age, 55.9 (11.8) years; 23 750 [74.9%] women). After insurance coverage initiation, there was substantial regional and temporal variation in adoption of sleeve gastrectomy. Prior-year state-level utilization of sleeve gastrectomy was highly associated with undergoing sleeve gastrectomy (Kleibergen-Paap Wald F statistic, 910.3). All but 2 patient characteristics (race and diagnosis of depression) were well-balanced between the top and bottom quartiles of the instrumental variable. Regarding 1-year outcomes, compared with patients undergoing gastric bypass, patients undergoing sleeve gastrectomy had a lower 1-year risk of mortality (0.9%; 95% CI, 0.8%-1.1% vs 1.7%; 95% CI, 1.3%-2.0%), complications (11.6%; 95% CI, 10.9%-12.3% vs 14.1%; 95% CI, 13.0%-15.3%), emergency department visits (48.3%; 95% CI, 46.9%-49.8% vs 53.6%; 95% CI, 52.3%-55.0%), hospitalization (23.4%; 95% CI, 22.4%-24.4% vs 26.5%; 95% CI, 25.1%-28.0%), and reinterventions (8.7%; 95% CI, 8.0%-9.4% vs 12.2%; 95% CI, 11.2%-13.3%). The risk of revision was not different between groups (0.6%; 95% CI, 0.3%-0.8% vs 0.4%; 95% CI, 0.3%-0.6%).

Conclusions and relevance: In this cross-sectional study of patients undergoing bariatric surgery, there was significant geographic variation in the use of sleeve gastrectomy following initiation of insurance coverage, which served as a strong instrument to compare 2 bariatric surgical procedures. This approach could be applied to other areas of health services research to serve as a complement to clinical trials.

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Conflict of interest statement

Conflict of Interest Disclosures: Dr Howard reported receiving grants from Blue Cross Blue Shield of Michigan Foundation and National Institute of Diabetes and Digestive and Kidney Diseases outside the submitted work. Dr Arterburn reported grants from the National Institute of Health Patient-Centered Outcomes Research Institute and Sharecare, Inc outside the submitted work. Dr Dimick reported founding and owning equity in ArborMetrix, Inc. No other disclosures were reported.

Figures

Figure.
Figure.. Change in Utilization of Sleeve Gastrectomy Among 10 Largest States From 2011-2017
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