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Editorial
. 2022 Aug 18;140(7):669-670.
doi: 10.1182/blood.2022017209.

Isn't it ironic: better RBCs by blocking iron

Nermi L Parrow  1 , Robert E Fleming  1
Affiliations
Editorial

Isn't it ironic: better RBCs by blocking iron

Nermi L Parrow et al. Blood. .
No abstract available

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Conflict of interest statement

Conflict-of-interest disclosure: R.E.F. is a member of the Scientific Advisory Board of Silence Therapeutics and receives research funding from Ultragenyx. R.E.F. and N.L.P. serve as consultants for Protagonist Therapeutics.

Comment on

References

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    1. Das N, Xie L, Ramakrishnan SK, Campbell A, Rivella S, Shah YM. Intestine-specific disruption of hypoxia-inducible factor (HIF)-2α improves anemia in sickle cell disease. J Biol Chem. 2015;290(39):23523-23527. - PMC - PubMed
    1. Parrow NL, Violet PC, George NA, et al. . Dietary iron restriction improves markers of disease severity in murine sickle cell anemia. Blood. 2021;137(11):1553-1555. - PMC - PubMed
    1. Manolova V, Nyffenegger N, Flace A, et al. . Oral ferroportin inhibitor ameliorates ineffective erythropoiesis in a model of β-thalassemia. J Clin Invest. 2019;130(1):491-506. - PMC - PubMed
    1. Drakesmith H, Nemeth E, Ganz T. Ironing out ferroportin. Cell Metab. 2015;22(5): 777-787. - PMC - PubMed