Toward preventing Parkinson's disease

Affiliations

¹ Department of Neurology, University Medical Center Göttingen and Paracelsus-Elena-Klinik, Kassel, Germany.
² Department of Geriatrics, University Medical Center, Göttingen, Germany.

Comment

Brit Mollenhauer et al. Science. 2022.

. 2022 Aug 19;377(6608):818-819.

doi: 10.1126/science.add7162. Epub 2022 Aug 18.

¹ Department of Neurology, University Medical Center Göttingen and Paracelsus-Elena-Klinik, Kassel, Germany.
² Department of Geriatrics, University Medical Center, Göttingen, Germany.

Abstract

A glycoprotein is a possible biomarker of pathogenic progression for Parkinson's disease.

GPNMB confers risk for Parkinson's disease through interaction with α-synuclein.
Diaz-Ortiz ME, Seo Y, Posavi M, Carceles Cordon M, Clark E, Jain N, Charan R, Gallagher MD, Unger TL, Amari N, Skrinak RT, Davila-Rivera R, Brody EM, Han N, Zack R, Van Deerlin VM, Tropea TF, Luk KC, Lee EB, Weintraub D, Chen-Plotkin AS. Diaz-Ortiz ME, et al. Science. 2022 Aug 19;377(6608):eabk0637. doi: 10.1126/science.abk0637. Epub 2022 Aug 19. Science. 2022. PMID: 35981040 Free PMC article.