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. 2022 Aug 18;12(8):e060555.
doi: 10.1136/bmjopen-2021-060555.

Why do people consent to receiving SARS-CoV-2 vaccinations? A representative survey in Germany

Harald Walach  1   2 , Michael Ofner  3   4 , Viviane Ruof  2 , Markus Herbig  5 , Rainer Johannes Klement  6
Affiliations

Why do people consent to receiving SARS-CoV-2 vaccinations? A representative survey in Germany

Harald Walach et al. BMJ Open. .

Abstract

Objective: To answer the question: Why do people consent to being vaccinated with novel vaccines against SARS-CoV-2?

Design: Representative survey.

Setting: Online panel.

Participants: 1032 respondents of the general German population.

Method: A representative survey among German citizens in November/December 2021 that resulted in 1032 complete responses on vaccination status, sociodemographic parameters and opinions about the COVID-19 situation.

Results: Almost 83% of the respondents were vaccinated. The major motivation was fear of medical consequences of an infection and the wish to lead a normal life again. The major motivation to be not vaccinated was the fear of side effects and scepticism about long-term effectiveness and safety. Sixteen per cent of vaccinated respondents reported some serious side effect, while more than 30% reported health improvements, mostly due to the relief of psychological stress and social reintegration. We also validated a 'Corona Orthodoxy Score-COS' consisting of seven items reflecting opinions on COVID-19. The scale is reliable (alpha=0.76) and unidimensional. The COS was a highly significant predictor of vaccination status and readiness to be vaccinated in a multivariable logistic regression model. Those who were vaccinated were more likely to live in smaller households (OR=0.82, p=0.024), had a higher income (OR=1.27, p<0.001), a higher COS score (OR 1.4, p<0.0001) and used less alternative media (OR=0.44, p=0.0024) and scientific publications (OR=0.42, p=0.011) as information sources.

Conclusions: The major motives for being vaccinated are fear of medical symptoms and the wish to lead a normal life. Those not wanting to be vaccinated cite a lack of knowledge regarding long-term safety and side effects as reasons. This can likely only be overcome by careful and active long-term efficacy and safety monitoring.

Keywords: COVID-19; health policy; immunology; public health.

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Conflict of interest statement

Competing interests: MH is the CEO of the company that conducted the survey. HW held an endowed chair sponsored by Heel pharmaceutical company, a producer of homeopathic remedies.

Figures

Figure 1
Figure 1
Receiver-operator-characteristics curves for model 1 (predicting vaccination status) and 2 (predicting willingness to be vaccinated).
See this image and copyright information in PMC

References

    1. MacDonald NE, SAGE Working Group on Vaccine Hesitancy . Vaccine hesitancy: definition, scope and determinants. Vaccine 2015;33:4161–4. 10.1016/j.vaccine.2015.04.036 - DOI - PubMed
    1. Stojanovic J, Boucher VG, Gagne M, et al. Global trends and correlates of COVID-19 vaccination Hesitancy: findings from the iCARE study. Vaccines 2021;9:661. 10.3390/vaccines9060661 - DOI - PMC - PubMed
    1. Fathalla Aboelsaad IA, Hafez DM, Almaghraby A. Systematic review and meta-analysis on COVID-19 vaccine Hesitancy. medRxiv 2021:2021.05.15.21257261.
    1. Savoia E, Su M, Piltch-Loeb R. Understanding COVID-19 vaccine early skepticism and misinformation. medRxiv 2021:2021.07.21.21260881. - PMC - PubMed
    1. Kerdoun MA, Henni AH, Yamoun A. COVID-19 vaccine hesitancy among Algerian medical students: a cross-sectional study in five universities. medRxiv 2021:2021.08.29.21261803.

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