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Editorial
. 2022 Aug 23;80(8):779-782.
doi: 10.1016/j.jacc.2022.06.010.

Medication Nonadherence: A Challenging Conundrum for Clinical Trials, Patients, and Clinicians

Usman Baber  1 , Michael J Blaha  2 , Roxana Mehran  3
Affiliations
Free article
Editorial

Medication Nonadherence: A Challenging Conundrum for Clinical Trials, Patients, and Clinicians

Usman Baber et al. J Am Coll Cardiol. .
Free article
No abstract available

Keywords: adherence; clinical trials; health outcomes.

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Conflict of interest statement

Funding Support and Author Disclosures Dr Baber has received honoraria from AstraZeneca and Amgen. Dr Blaha has received grants from the National Institutes of Health, U.S. Food and Drug Administration, American Heart Association, Aetna Foundation, Amgen Foundation, and Novo Nordisk; and has received personal fees from Sanofi, Regeneron, Novartis, Bayer, Akcea, 89Bio, Kaleido, Inozyme, Kowa, Roche, and VoxelCloud outside the submitted work. Dr Mehran has received grants from Abbott Laboratories, AstraZeneca, Bayer, Beth Israel Deaconess, Bristol Myers Squibb, CSL Behring, Daiichi-Sankyo, Medtronic, Novartis Pharmaceuticals, and OrbusNeich; has received personal fees from Abbott Laboratories, Boston Scientific, Medscape/WebMD, Siemens Medical Solutions, PLx Opco dba PLx Pharma, Roivant Sciences, Sanofi, Medtelligence (Janssen Scientific Affairs), and Janssen Scientific Affairs; has received other compensation from Abbott Laboratories, Abiomed, Bristol Myers Squibb, Claret Medical, Elixir Medical, The Medicines Company, Spectranetics/Philips/Volcano, and Watermark Research Partners; and has received nonfinancial support and other compensation from Regeneron Pharmaceuticals and Idorsia Pharmaceuticals.

Comment on

  • Association of Medication Adherence With Health Outcomes in the ISCHEMIA Trial.
    Garcia RA, Spertus JA, Benton MC, Jones PG, Mark DB, Newman JD, Bangalore S, Boden WE, Stone GW, Reynolds HR, Hochman JS, Maron DJ; ISCHEMIA Research Group. Garcia RA, et al. J Am Coll Cardiol. 2022 Aug 23;80(8):755-765. doi: 10.1016/j.jacc.2022.05.045. J Am Coll Cardiol. 2022. PMID: 35981820 Free PMC article. Clinical Trial.
  • Impact of Medication Nonadherence in a Clinical Trial of Dual Antiplatelet Therapy.
    Valgimigli M, Frigoli E, Vranckx P, Ozaki Y, Morice MC, Chevalier B, Onuma Y, Windecker S, Delorme L, Kala P, Kedev S, Abhaichand RK, Velchev V, Dewilde W, Podolec J, Leibundgut G, Topic D, Schultz C, Stankovic G, Lee A, Johnson T, Tonino PAL, Klotzka A, Lesiak M, Lopes RD, Smits PC, Heg D; MASTER DAPT Investigators. Valgimigli M, et al. J Am Coll Cardiol. 2022 Aug 23;80(8):766-778. doi: 10.1016/j.jacc.2022.04.065. J Am Coll Cardiol. 2022. PMID: 35981821 Clinical Trial.

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