Bacterial histamine and abdominal pain in IBS

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Comment

Katrina Ray. Nat Rev Gastroenterol Hepatol. 2022 Oct.

. 2022 Oct;19(10):623.

doi: 10.1038/s41575-022-00681-z.

No abstract available

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Histamine production by the gut microbiota induces visceral hyperalgesia through histamine 4 receptor signaling in mice.
De Palma G, Shimbori C, Reed DE, Yu Y, Rabbia V, Lu J, Jimenez-Vargas N, Sessenwein J, Lopez-Lopez C, Pigrau M, Jaramillo-Polanco J, Zhang Y, Baerg L, Manzar A, Pujo J, Bai X, Pinto-Sanchez MI, Caminero A, Madsen K, Surette MG, Beyak M, Lomax AE, Verdu EF, Collins SM, Vanner SJ, Bercik P. De Palma G, et al. Sci Transl Med. 2022 Jul 27;14(655):eabj1895. doi: 10.1126/scitranslmed.abj1895. Epub 2022 Jul 27. Sci Transl Med. 2022. PMID: 35895832

1. De Palma, G. et al. Histamine production by the gut microbiota induces visceral hyperalgesia through histamine 4 receptor signalling in mice. Sci. Transl Med. 14, eabj1895 (2022) - DOI