Recurrent Cellulitis: Who is at Risk and How Effective is Antibiotic Prophylaxis?
- PMID: 35983462
- PMCID: PMC9379124
- DOI: 10.2147/IJGM.S326459
Recurrent Cellulitis: Who is at Risk and How Effective is Antibiotic Prophylaxis?
Abstract
Recurrent cellulitis following successful treatment is common and prevention should be a major component in the management of cellulitis. Conditions that increase the risk of recurrence include chronic edema, venous disease, dermatomycosis and obesity. These risk factors should be actively managed as further episodes of cellulitis increases the risk of recurrence. The role of non-antibiotic measures is important and should be first-line in prevention. Antibiotic prophylaxis is effective, but its role is limited to non-purulent cellulitis where risk factors are appropriately managed.
Keywords: antibiotic prophylaxis; cellulitis; edema; recurrence; risk factors; venous insufficiency.
© 2022 Ong et al.
Conflict of interest statement
The authors report no conflicts of interest in this work.
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References
-
- Osborn CE. Benchmarking with national ICD-9-CM coded data. J AHIMA. 1999;70(3):59–69. - PubMed
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