The authors reply

Heder J de Vries¹, Harm Jan de Grooth¹, Leo M Heunks^{1

2}

Affiliations

¹ Department of Intensive Care, Amsterdam UMC location VUmc, Amsterdam, The Netherlands.
² Department of Intensive Care, Erasmus MC, Rotterdam, The Netherlands.

Comment

Heder J de Vries et al. Crit Care Med. 2022.

. 2022 Sep 1;50(9):e732-e734.

doi: 10.1097/CCM.0000000000005598. Epub 2022 Aug 15.

Heder J de Vries¹, Harm Jan de Grooth¹, Leo M Heunks^{1

2}

¹ Department of Intensive Care, Amsterdam UMC location VUmc, Amsterdam, The Netherlands.
² Department of Intensive Care, Erasmus MC, Rotterdam, The Netherlands.

No abstract available

Conflict of interest statement

The authors have disclosed that they do not have any potential conflicts of interest.

Proof of Concept, Feasibility, and Efficacy Trials.
Chandelia S. Chandelia S. Crit Care Med. 2022 Sep 1;50(9):e731-e732. doi: 10.1097/CCM.0000000000005581. Epub 2022 Aug 15. Crit Care Med. 2022. PMID: 35984068 No abstract available.

1. Chandelia S: Proof of Concept, Feasibility, and Efficacy Trials. Crit Care Med 2022; 50:e731–e732
1. de Vries HJ, Jonkman AH, de Grooth HJ, et al.: Lung- and diaphragm-protective ventilation by titrating inspiratory support to diaphragm effort: A randomized clinical trial. Crit Care Med 2022; 50:192–203
1. Singal AG, Higgins PD, Waljee AK: A primer on effectiveness and efficacy trials. Clin Transl Gastroenterol 2014; 5:e45
1. Goligher EC, Ranieri VM, Slutsky AS: Is severe COVID-19 pneumonia a typical or atypical form of ARDS? And does it matter? Intensive Care Med 2021; 47:83–85
1. Goligher EC, Dres M, Patel BK, et al.: Lung- and diaphragm-protective ventilation. Am J Respir Crit Care Med 2020; 202:950–961