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. 2022 Sep 1;163(9):1670-1674.
doi: 10.1097/j.pain.0000000000002583. Epub 2022 Jan 17.

A new way of thinking about pains

John D Loeser  1
Affiliations

A new way of thinking about pains

John D Loeser. Pain. .

Abstract

The traditional construct of acute pain vs chronic pain is arbitrary and obscures fundamental differences in clinical pain phenomena. A more powerful dichotomy between peripherally generated pain and centrally maintained pains can facilitate advances in both pain research and clinical care. We should abandon the temporally based pain classification scheme because it does not accurately reflect the underlying principles inherent in the phenomena of pain.

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References

    1. Aydede M, Shriver A. Recently introduced definition of “nociplastic pain” by the International Association for the Study of Pain needs better formulation. PAIN 2018;159:1176–7.
    1. Baliki MN, Apkarian AV. Nociception, pain, negative moods, and behavior selection. Neuron 2015;87:474–91.
    1. Bonica JJ. The management of pain. Philadelphia: Lea and Febiger, 1953. p. 25.
    1. Borsook D, Youssef AM, Simons L, Elman I, Eccleston C. When pain gets stuck: the evolution of pain chronification and treatment resistance. PAIN 2018;159:2421–36.
    1. Brummett CM, Urquhart AG, Hassett AL, Tsodikov A, Hallstrom BR, Wood NI, Williams DA, Clauw DJ. Characteristics of fibromyalgia independently predict poorer long-term analgesic outcomes following total knee and hip arthroplasty. Arthritis Rheumatol 2015;67:1386–94.

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