Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2023 Feb;98(2):270-272.
doi: 10.1111/cen.14816. Epub 2022 Aug 30.

Letter to the editor of clinical endocrinology: Assessment of adrenal function in patients who survive COVID-19

Affiliations
Comment

Letter to the editor of clinical endocrinology: Assessment of adrenal function in patients who survive COVID-19

Sophie A Clarke et al. Clin Endocrinol (Oxf). 2023 Feb.
No abstract available

Keywords: COVID-19; adrenal cortex hormones; adrenal insufficiency; mineralocorticoids.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Dihydroepiandrosterone (DHEAS) and peak cortisol levels following administration of Synacthen (Tetracosactide) 250 μg in survivors of COVID‐19 ≥3 months after initial presentation. (A) Individual peak cortisol (nmol/L) levels and baseline DHEAS values (μmol/L) following administration of Synacthen (tetracosactide) 250 μg are presented for patients for whom data is available (n = 68). (B) Individual DHEAS values are presented for those patients with persistent fatigue ≥3 months after initial presentation with COVID‐19 (n = 42) and those without persistent fatigue (n = 26).

Comment on

  • COVID-19 targets human adrenal glands.
    Kanczkowski W, Evert K, Stadtmüller M, Haberecker M, Laks L, Chen LS, Frontzek K, Pablik J, Hantel C, Beuschlein F, Kurth T, Gruber S, Aguzzi A, Varga Z, Bornstein SR. Kanczkowski W, et al. Lancet Diabetes Endocrinol. 2022 Jan;10(1):13-16. doi: 10.1016/S2213-8587(21)00291-6. Epub 2021 Nov 18. Lancet Diabetes Endocrinol. 2022. PMID: 34801110 Free PMC article. No abstract available.

References

    1. Ayoubkhani D. Prevalence of ongoing symptoms following coronavirus (COVID‐19) infection in the UK: 6 January 2022. Off Natl Stat . 2022:1‐16. https://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/...
    1. Taquet M, Dercon Q, Luciano S, Geddes JR, Husain M, Harrison PJ. Incidence, co‐occurrence, and evolution of long‐COVID features: a 6‐month retrospective cohort study of 273,618 survivors of COVID‐19. PLoS Med. 2021;18(9):1‐22. 10.1371/journal.pmed.1003773 - DOI - PMC - PubMed
    1. Kanczkowski W, Evert K, Stadtmüller M, et al. COVID‐19 targets human adrenal glands. Lancet Diabetes Endocrinol. 2021;8587(21):19‐21. 10.1016/s2213-8587(21)00291-6 - DOI - PMC - PubMed
    1. Mao Y, Xu B, Guan W, Xu D, Li F, Ren R. The adrenal cortex, an underestimated site of SARS‐CoV‐2 infection. Front Endocrinol. 2021;11(January):1‐10. 10.3389/fendo.2020.593179 - DOI - PMC - PubMed
    1. Elkhouly MMN, Elazzab AA, Moghul SS. Bilateral adrenal hemorrhage in a man with severe COVID‐19 pneumonia. Radiol Case Rep. 2021;16(6):1438‐1442. 10.1016/j.radcr.2021.03.032 - DOI - PMC - PubMed