Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2022 Oct;24(10):1487-1494.
doi: 10.1007/s11886-022-01768-4. Epub 2022 Aug 20.

Imaging Evaluation of Kawasaki Disease

Affiliations
Review

Imaging Evaluation of Kawasaki Disease

Pei-Ni Jone et al. Curr Cardiol Rep. 2022 Oct.

Abstract

Purpose of review: This review provides the summary of the appropriate use of these modalities when caring for patients with Kawasaki disease at diagnosis and for long-term management.

Recent findings: Kawasaki disease is an inflammatory syndrome of unknown etiology that can result in coronary artery dilations or aneurysms if left untreated in 25% of the patients and 3-5% in treated patients. In addition to coronary artery aneurysms, patients can have ventricular dysfunction, valvular regurgitation, aortic root dilation, and pericardial effusion due to inflammation of the myocardium. Noninvasive imaging modalities are important to these assessments. Echocardiography is the first-line noninvasive evaluation of coronaries and function. Cardiac magnetic resonance imaging is useful for functional assessment in long-term follow-up. Distal coronaries, thromboses, and stenoses are best evaluated by cardiac computed tomography. Future research should demonstrate the effectiveness of advanced functional imaging in patients with Kawasaki disease and decreased radiation from cardiac computed tomography.

Keywords: Cardiac magnetic resonance imaging; Computer tomography; Coronary imaging; Echocardiography; Function assessment; Kawasaki disease.

PubMed Disclaimer

References

Papers of particular interest, published recently, have been highlighted as: • Of importance
    1. • McCrindle BW, Rowley AH, Newburger JW, Burns JC, Bolger AF, Gewitz M, et al. Diagnosis, treatment, and long-term management of Kawasaki disease: a scientific statement for health professionals from the American Heart Association. Circulation. 2017;135(17):e927–99. https://doi.org/10.1161/CIR.0000000000000484 . Important review article in Kawasaki disease. - DOI - PubMed
    1. • Printz BF, Sleeper LA, Newburger JW, Minich LL, Bradley T, Cohen MS, et al. Noncoronary cardiac abnormalities are associated with coronary artery dilation and with laboratory inflammatory markers in acute Kawasaki disease. J Am Coll Cardiol. 2011;57(1):86–92. https://doi.org/10.1016/j.jacc.2010.08.619 . Echocardiographic parameters to read in Kawasaki disease. - DOI - PubMed - PMC
    1. Brown LM, Duffy CE, Mitchell C, Young L. A practical guide to pediatric coronary artery imaging with echocardiography. J Am Soc Echocardiogr. 2015;28(4):379–91. https://doi.org/10.1016/j.echo.2015.01.008 . - DOI - PubMed
    1. Phadke D, Patel SS, Dominguez SR, Heizer H, Anderson MS, Glode MP, et al. Tissue Doppler imaging as a predictor of immunoglobulin resistance in Kawasaki disease. Pediatr Cardiol. 2015;36(8):1618–23. https://doi.org/10.1007/s00246-015-1206-5 . - DOI - PubMed
    1. McCandless RT, Minich LL, Wilkinson SE, McFadden ML, Tani LY, Menon SC. Myocardial strain and strain rate in Kawasaki disease. Eur Heart J Cardiovasc Imaging. 2013;14(11):1061–8. https://doi.org/10.1093/ehjci/jet041 . - DOI - PubMed

MeSH terms

LinkOut - more resources