"C-reactive protein levels and risk of dementia": Subgroup analyses in Mendelian randomization are likely to be misleading
- PMID: 35988060
- PMCID: PMC10087214
- DOI: 10.1002/alz.12743
"C-reactive protein levels and risk of dementia": Subgroup analyses in Mendelian randomization are likely to be misleading
Conflict of interest statement
None. Author disclosures are available in the supporting information.
Comment in
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Observational and genetic studies of C-reactive protein levels and risk of Alzheimer's disease.Alzheimers Dement. 2022 Dec;18(12):2734-2735. doi: 10.1002/alz.12742. Epub 2022 Aug 21. Alzheimers Dement. 2022. PMID: 35988061 No abstract available.
References
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- Hegazy SH, Thomassen JQ, Rasmussen IJ, Nordestgaard BG, Tybjærg‐Hansen A, Frikke‐Schmidt R. C‐reactive protein levels and risk of dementia – Observational and genetic studies of 111,242 individuals from the general population. Alzheimers Dementia. 2022;18(11):2262‐2271. 10.1002/alz.12568 - DOI - PMC - PubMed
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- Yusuf S, Wittes J, Probstfield J, Tyroler HA. Analysis and interpretation of treatment effects in subgroups of patients in randomized clinical trials. JAMA. 1991;266(1):93‐98. - PubMed
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