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Case Reports
. 2022 Jul 19;14(7):e27008.
doi: 10.7759/cureus.27008. eCollection 2022 Jul.

Binocular Diplopia: An Unusual Presentation of Squamous Cell Carcinoma of the Lung

Kyle Sugg  1 , Waseem Diab  2 , Aditi Kappagantu  2 , Omid Yazdanpanah  2
Affiliations
Case Reports

Binocular Diplopia: An Unusual Presentation of Squamous Cell Carcinoma of the Lung

Kyle Sugg et al. Cureus. .

Abstract

Here, we discuss the case of a 72-year-old male with a known history of COPD who presented with one month of binocular diplopia and headache. The initial clinical investigation discovered destructive intraosseous lesions within the sellar and para-sellar (SPS) regions, suggesting primary versus metastatic intracranial lesions. Further examination revealed a mass in the right lung, with subsequent biopsy confirming squamous cell carcinoma (SCC) of the lung as the primary site of malignancy. The SPS regions of the basicranium, while well-documented to be associated with various primary neoplasms, rarely serve as sites of metastasis. Throughout this article, we will review the pathophysiology of squamous cell lung cancer, current understandings of SPS metastasis, and considerations of metastatic lung SCC management.

Keywords: binocular diplopia; metastatic squamous cell carcinoma; sellar metastasis; squamous cell carcinoma of the lung; squamous cell lung carcinoma.

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. Sagittal MRI of the metastatic lesion abutting the optic chiasm (arrow).
Figure 2
Figure 2. Axial chest CT demonstrating the presence of a right upper lobe spiculated mass (arrow).
Figure 3
Figure 3. Core needle biopsy (CT-guided) of the right lung mass (arrow).
See this image and copyright information in PMC

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