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. 2022 Aug 18;14(8):e28125.
doi: 10.7759/cureus.28125. eCollection 2022 Aug.

Evaluation of the Effectiveness of Probiotic Mouthwashes in Reducing Dental Plaque in Primary and Permanent Teeth: A Randomized Clinical Trial

Enas Alhallak  1 , Chaza Kouchaje  1 , Ahmad Hasan  2 , Ramah Makieh  1
Affiliations

Evaluation of the Effectiveness of Probiotic Mouthwashes in Reducing Dental Plaque in Primary and Permanent Teeth: A Randomized Clinical Trial

Enas Alhallak et al. Cureus. .

Abstract

Background: Due to the disadvantages of chemical mouthwashes, the search for an effective and safe anti-plaque agent has led to the emergence of probiotics.

Aim: To compare the effectiveness of nonchemical mouthwashes (probiotic) with chemical mouthwashes (fluoride) on plaque accumulation in orphan children after seven, 14, and 30 days of use.

Materials and methods: The present study was a triple-blind randomized controlled trial with two parallel groups (A and B), which included 30 healthy children. Each group included 15 children aged between eight and 10 years from Dar Al-Rahma Orphanage in Damascus, Syrian Arab Republic. Group A used 10 ml of probiotic mouthwash (ProbioClean) and group B used 10 ml of fluoride mouthwash (Colgate) for 60 seconds for 30 days. Turesky Modified Quigley-Hein (TMQH) plaque index was used in this study to record the values of plaque accumulation on days seven, 14, and 30.

Results: Mann-Whitney U test showed statistical significance between probiotics and fluoride mouthwashes on days 14 (p < 0.001) and 30 (p = 0.001), and there was no statistical significance on day seven (p = 0.934).

Conclusion: According to the results of this study, probiotic mouthwashes are considered an effective solution for maintaining oral health. However, probiotics are more effective in reducing plaque accumulation after a month of use.

Keywords: dental plaque; fluoride; mouthwashes; orphan children; probiotic.

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. Quigley-Hein plaque index
Adapted from: Chinger G, Hadidjah D, Rusminah N. (2012). Comparison effectiveness between cetylpyridinium chloride and triclosan mouthwash on plaque. Padjadjaran Journal of Dentistry, 24(3). doi: http://dx.doi.org/10.24198/pjd.vol24no3.26838. Under Creative Commons Attribution 4.0 International License.
See this image and copyright information in PMC

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