Rhabdomyolysis after BNT162b2 mRNA Covid-19 vaccine in an adolescent male
- PMID: 35991822
- PMCID: PMC9356520
- DOI: 10.4314/mmj.v34i2.13
Rhabdomyolysis after BNT162b2 mRNA Covid-19 vaccine in an adolescent male
Abstract
Pfizer-BioNTech COVID-19 (BNT162b2) conferred a high level of protection against Covid-19 with a proven short-term safety profile. Although cases of vaccine-associated myopericarditis have been reported, the existence of rhabdomyolysis without myocarditis has not yet been published. A 16-year-old, healthy male patient, who did not use any herbal or illegal drugs before, was admitted with muscle pain that developed after the second dose of BNT162b2 vaccine. Cardiac examination and heart enzymes were normal and the patient had significantly higher creatinine kinase levels. The patient, whose enzymes returned to normal with only force hydration therapy, recovered without complications. Reporting the side effects of the vaccine, which has a short history of application to large populations, is of vital importance in the conduct of vaccine development studies and in identifying the risky group in terms of side effects.
Keywords: Pfizer-BioNTech COVID-19; adolescent; rhabdomyolysis.
© 2022 The College of Medicine and the Medical Association of Malawi.
References
-
- Emergency use authorization: Pfizer-BioNTech COVID-19 vaccine. Silver Spring, MD: Food and Drug Administration; 2021. Available from: https://www.fda.gov/emergencypreparedness-and-response/coronavirus-disea....
-
- Food and Drug Administration, author. Pfizer-BioNTech COVID-19 vaccine EUA amendment review memorandum. Silver Spring, MD: US Department of Health and Human Services, Food and Drug Administration; 2021. Available from: https://www.fda.gov/media.
-
- Gargano JW, Wallace M, Hadler SC, et al. Use of mRNA COVID-19 vaccine after reports of myocarditis among vaccine recipients: update from the Advisory Committee on Immunization Practices—United States, June 2021. MMWR Morb Mortal Wkly Rep. 2021;70:977–982. doi: 10.15585/mmwr.mm7027e2. Available from: - DOI - PMC - PubMed
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical