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. 2022 Aug 5:80:104333.
doi: 10.1016/j.amsu.2022.104333. eCollection 2022 Aug.

Validation of R-hf risk score for risk stratification in ischemic heart failure patients: A prospective cohort study

Rajesh Rajan  1   2 , Suman Omana Soman  3 , Mohammed Al Jarallah  1 , Zhanna Kobalava  2 , Raja Dashti  1 , Ibrahim Al Zakwani  4   5 , Joud Al Balool  6 , Gary Tse  7 , Parul Setiya  8 , Peter A Brady  9 , Ahmad Al-Saber  10 , Govindan Vijayaraghavan  11
Affiliations

Validation of R-hf risk score for risk stratification in ischemic heart failure patients: A prospective cohort study

Rajesh Rajan et al. Ann Med Surg (Lond). .

Abstract

Background: The aim of this study was to validate R-heart failure (R-hf) risk score in ischemic heart failure patients.

Methods: We prospectively recruited a cohort of 179 ischemic and 107 non-ischemic heart failure patients. This study mainly focused on ischemic heart failure patients. Non-ischemic heart failure patients were included for the purpose of validation of the risk score in various heart failure groups. Patients were stratified in high risk, moderate risk and low risk groups according to R-hf risk score.

Results: A total of 179 participants with ischemic heart failure were included. Based on R-hf risk score, 82 had high risk, 50 had moderate risk and 47 had low risk heart failure scores. More than half of the patients having R-hf score of <5 had renal failure (n = 91, 50.8%) and anemia (n = 99, 55.3%). Notably, HFrEF was more prevalent in patients with high risk score (74, 90.2%). Patients with high risk score had significantly higher creatinine (2.63 ± 1.96, p < 0.001), Troponin-T HS (59.9 ± 38.0, p < 0.001) and PRO BNP (17842 ± 6684, p < 0.001) when compared to patients with low and moderate risk score. Patients with low risk score had significantly higher Hb (13.2 ± 1.85, p < 0.001), Albumin (3.69 ± 0.42, p < 0.001) and GFR (90.0 ± 8.04, p < 0.001). A R-hf score of <5 was a significant predictor of mortality in ischemic (OR = 50.34; 95% CI [16.94-194.00, p < 0.001) and non-ischemic (OR = 46.34; 95% CI [12.97-225.39], p < 0.001) heart failure patients.

Conclusions: Lower R-hf risk score is a significant predictor of mortality in ischemic and non-ischemic heart failure patients. Risk score can be accessed at https://www.hfriskcalc.in.

Keywords: Chronic kidney disease; Ischemic heart failure; Left ventricular dysfunction; Mortality; R-Hf risk score.

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Conflict of interest statement

The authors declare that they have no competing interests.

Figures

Fig. 1
Fig. 1
Flowchart demonstrates population enrollment.
Fig. 2
Fig. 2
Illustrates the results of association of Rhf-score with ejection fraction for the group of alive and dead patients.
Fig. 3
Fig. 3
Illustrates the results of association of Rhf-score with PRO BNP for the group of alive and dead patients.
See this image and copyright information in PMC

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