[Host and environmental risk factors of ovarian cancer]

Abstract

A case-control study of 65 women with ovarian epithelial carcinoma and 130 individually age-matched controls were conducted from 1985 to 1986 in Hokkaido. The following factors were significantly greater in the cases than in the controls: higher prevalence of breast, uterine, or ovarian cancer of their mother or sister; nulliparous; less experience in induced abortion; less frequent ligation of Fallopian tubes; irregular menstruation around at 20 years of age; past history of pathological amenorrhea in the premenopausal group; daily meat or fish consumption in the postmenopausal group. It is inferred that women with ovarian cancer had a genetical predisposition and dysfunctional ovaries from early in the life.