Virgin coconut oil: A comprehensive review of antioxidant activity and mechanisms contributed by phenolic compounds
- PMID: 35997296
- DOI: 10.1080/10408398.2022.2113361
Virgin coconut oil: A comprehensive review of antioxidant activity and mechanisms contributed by phenolic compounds
Abstract
Virgin coconut oil (VCO) is obtained by processing mature coconut cores with mechanical or natural methods. In recent years, VCO has been widely used in the food, pharmaceutical, and cosmetic industries because of its excellent functional activities. VCO has biological functions such as antioxidant, anti-inflammatory, antibacterial, and antiviral, and also has potential therapeutic effects on many chronic degenerative diseases. Among these functions, the antioxidant is the most basic and important function, which is mainly determined by phenolic compounds and medium-chain fatty acids (MCFAs). This review aims to elucidate the antioxidant functions of each phenolic compound in VCO, and discuss the antioxidant mechanisms of VCO in terms of the role of phenolic compounds with fat, intestinal microorganisms, and various organs. Besides, the composition of VCO and its application in various industries are summarized, and the biological functions of VCO are generalized, which should lay a foundation for further research on the antioxidant activity of VCO and provide a theoretical basis for the development of food additives with antioxidant activity.
Keywords: Virgin coconut oil; antioxidant; mechanism; phenolic compounds.
Similar articles
-
Variations in natural polyphenols determine the anti-inflammatory potential of virgin coconut oils.J Food Sci. 2021 May;86(5):1620-1628. doi: 10.1111/1750-3841.15705. Epub 2021 Apr 16. J Food Sci. 2021. PMID: 33864246
-
Virgin coconut oil complements with its polyphenol components mitigate sodium fluoride toxicity in vitro and in vivo.Drug Chem Toxicol. 2022 Nov;45(6):2528-2534. doi: 10.1080/01480545.2021.1962691. Epub 2021 Aug 18. Drug Chem Toxicol. 2022. PMID: 34407699
-
In Vitro Anticancer Activity of Virgin Coconut Oil and its Fractions in Liver and Oral Cancer Cells.Anticancer Agents Med Chem. 2019;19(18):2223-2230. doi: 10.2174/1871520619666191021160752. Anticancer Agents Med Chem. 2019. PMID: 31736449
-
Virgin Coconut Oil and its Cardiovascular Health Benefits.Nat Prod Commun. 2016 Aug;11(8):1151-1152. Nat Prod Commun. 2016. PMID: 30725578
-
Coconut Milk and Coconut Oil: Their Manufacture Associated with Protein Functionality.J Food Sci. 2018 Aug;83(8):2019-2027. doi: 10.1111/1750-3841.14223. Epub 2018 Jul 13. J Food Sci. 2018. PMID: 30004125 Review.
Cited by
-
Fisetin Attenuates Zinc Overload-Induced Hepatotoxicity in Mice via Autophagy-Dependent Nrf2 Activation.Int J Mol Sci. 2025 May 22;26(11):4978. doi: 10.3390/ijms26114978. Int J Mol Sci. 2025. PMID: 40507790 Free PMC article.
-
Evaluation of the therapeutic potential of novel nanoparticle formulations of glutathione and virgin coconut oil in an experimental model of carbon tetrachloride-induced liver failure.BMC Pharmacol Toxicol. 2024 Oct 8;25(1):74. doi: 10.1186/s40360-024-00795-x. BMC Pharmacol Toxicol. 2024. PMID: 39380023 Free PMC article.
-
Composition, distribution, and bioactivity of polyphenols in pineapple Fibers: Insights from UHPLC-MS analysis for the development of antibacterial materials.Curr Res Food Sci. 2025 May 7;10:101069. doi: 10.1016/j.crfs.2025.101069. eCollection 2025. Curr Res Food Sci. 2025. PMID: 40503525 Free PMC article.
-
Anti-inflammatory and antimicrobial efficacy of coconut oil for periodontal pathogens: a triple-blind randomized clinical trial.Clin Oral Investig. 2025 Mar 14;29(4):182. doi: 10.1007/s00784-025-06267-8. Clin Oral Investig. 2025. PMID: 40085302 Free PMC article. Clinical Trial.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical