Declaration of competing interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: Ronald Goldenberg reports a relationship with Astra Zeneca that includes: consulting or advisory, funding grants, and speaking and lecture fees. Ronald Goldenberg reports a relationship with Eli Lilly that includes: consulting or advisory, funding grants, and speaking and lecture fees. Ronald Goldenberg reports a relationship with Novo Nordisk Inc. that includes: consulting or advisory, funding grants, and speaking and lecture fees. Ronald Goldenberg reports a relationship with Sanofi that includes: consulting or advisory, funding grants, and speaking and lecture fees.