Communicating Precision Medicine Research: Multidisciplinary Teams and Diverse Communities

Julie A Beans¹, Susan B Trinidad², Erika Blacksher³, Vanessa Y Hiratsuka^{1

4}, Paul Spicer⁵, Erica L Woodahl⁶, Bert B Boyer⁷, Cecil M Lewis Jr^{5

8}, Patrick M Gaffney⁹, Nanibaa' A Garrison^{10

11

12}, Wylie Burke²

Affiliations

¹ Research Department, Southcentral Foundation, Anchorage, Alaska, USA.
² Department of Bioethics and Humanities, University of Washington, Seattle, Washington, USA.
³ Department of History and Philosophy of Medicine, University of Kansas City Medical Center, Kansas City, Kansas, United States of America Center for Practical Bioethics, Kansas City, Missouri, USA.
⁴ Center for Human Development, University of Alaska Anchorage, Anchorage, Alaska, USA.
⁵ Department of Anthropology, University of Oklahoma, Norman, Oklahoma, USA.
⁶ Department of Biomedical and Pharmaceutical Sciences, University of Montana, Missoula, Montana, USA.
⁷ Department of Obstetrics and Gynecology, Oregon Health & Sciences University, Portland, Oregon, USA.
⁸ Laboratories of Molecular Anthropology and Microbiome Research, University of Oklahoma, Norman, Oklahoma, USA.
⁹ Genes and Human Disease Research Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, USA.
¹⁰ Institute for Society and Genetics, University of California, Los Angeles, Los Angeles, California, USA.
¹¹ Institute for Precision Health, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, USA.
¹² Division of General Internal Medicine and Health Services Research, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, USA.

PMID: 35998578
PMCID: PMC9947193
DOI: 10.1159/000525684

Communicating Precision Medicine Research: Multidisciplinary Teams and Diverse Communities

Julie A Beans et al. Public Health Genomics. 2022.

. 2022 Aug 23:1-9.

doi: 10.1159/000525684. Online ahead of print.

Authors

Affiliations

¹ Research Department, Southcentral Foundation, Anchorage, Alaska, USA.
² Department of Bioethics and Humanities, University of Washington, Seattle, Washington, USA.
³ Department of History and Philosophy of Medicine, University of Kansas City Medical Center, Kansas City, Kansas, United States of America Center for Practical Bioethics, Kansas City, Missouri, USA.
⁴ Center for Human Development, University of Alaska Anchorage, Anchorage, Alaska, USA.
⁵ Department of Anthropology, University of Oklahoma, Norman, Oklahoma, USA.
⁶ Department of Biomedical and Pharmaceutical Sciences, University of Montana, Missoula, Montana, USA.
⁷ Department of Obstetrics and Gynecology, Oregon Health & Sciences University, Portland, Oregon, USA.
⁸ Laboratories of Molecular Anthropology and Microbiome Research, University of Oklahoma, Norman, Oklahoma, USA.
⁹ Genes and Human Disease Research Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, USA.
¹⁰ Institute for Society and Genetics, University of California, Los Angeles, Los Angeles, California, USA.
¹¹ Institute for Precision Health, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, USA.
¹² Division of General Internal Medicine and Health Services Research, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, USA.

PMID: 35998578
PMCID: PMC9947193
DOI: 10.1159/000525684

Abstract

Introduction: Precision medicine research investigates the differences in individuals' genetics, environment, and lifestyle to tailor health prevention and treatment options as part of an emerging model of health care delivery. Advancing precision medicine research will require effective communication across a wide range of scientific and health care disciplines and with research participants who represent diverse segments of the population.

Methods: A multidisciplinary group convened over the course of a year and developed precision medicine research case examples to facilitate precision medicine research discussions with communities.

Results: A shared definition of precision medicine research as well as six case examples of precision medicine research involving genetic risk, pharmacogenetics, epigenetics, the microbiome, mobile health, and electronic health records were developed.

Discussion/conclusion: The precision medicine research definition and case examples can be used as planning tools to establish a shared understanding of the scope of precision medicine research across multidisciplinary teams and with the diverse communities in which precision medicine research will take place. This shared understanding is vital for successful and equitable progress in precision medicine.

Keywords: Education in genetics; Genetic communication; Multidisciplinary team; Precision medicine; Risk communication.

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Conflict of interest statement

Conflict of Interest Statement

The authors have no conflicts of interest to declare.

References

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Communicating Precision Medicine Research: Multidisciplinary Teams and Diverse Communities

Affiliations

Communicating Precision Medicine Research: Multidisciplinary Teams and Diverse Communities

Authors

Affiliations

Abstract

Conflict of interest statement

References

Grants and funding

LinkOut - more resources

Full Text Sources