Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2022 Aug 22;32(16):R891-R894.
doi: 10.1016/j.cub.2022.07.025.

Cell death: All roads lead to mitochondria

Alexander Poltorak  1
Affiliations
Free article
Comment

Cell death: All roads lead to mitochondria

Alexander Poltorak. Curr Biol. .
Free article

Abstract

Mitochondria are central to apoptosis, an immunologically silent form of cell death. The mitochondrial, or 'intrinsic', apoptotic pathway is activated when the permeabilized mitochondrial membrane of stressed cells releases apoptotic effectors. A new study now characterizes how mitochondria are involved in the switch from pyroptotic to necroptotic cell death.

PubMed Disclaimer

Conflict of interest statement

Declaration of interests The author declares no competing interests.

Comment on

MeSH terms

LinkOut - more resources