Reassuring data regarding the use of hormone therapy at menopause and risk of breast cancer
- PMID: 35998670
- DOI: 10.1097/GME.0000000000002057
Reassuring data regarding the use of hormone therapy at menopause and risk of breast cancer
Conflict of interest statement
Financial disclosure/conflicts of interest: J.V.P. reports participating in a multicenter clinical trial on nonhormone therapy for hot flashes, for which the University of Virginia received financial support from Bayer. A.M.K. reports that his institution receives financial support from Merck and Bayer for ongoing clinical trials. C.S.W. has nothing to disclose.
Comment on
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Estrogen therapy and breast cancer in randomized clinical trials: a narrative review.Menopause. 2022 Sep 1;29(9):1086-1092. doi: 10.1097/GME.0000000000002021. Epub 2022 Aug 16. Menopause. 2022. PMID: 35969882 Review.
References
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- Anderson GL, Limacher M, Assaf AR, et al. Effects of conjugated equine estrogen in postmenopausal women with hysterectomy: the women's health initiative randomized controlled trial. JAMA 2004;291:1701–1712. doi: 10.1001/jama.291.14.1701 - DOI
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- Chlebowski RT, Hendrix SL, Langer RD, et al. Influence of estrogen plus progestin on breast, cancer and mammography in healthy postmenopausal women: the women's health initiative randomized trial. JAMA 2003;289:3243–3253. doi: 10.1001/jama.289.24.3243 - DOI
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- Chlebowski RT, Rohan TE, Manson JE, et al. Breast cancer after use of estrogen plus progestin and estrogen alone: analyses of data from 2 women's health initiative randomized clinical trials. JAMA Oncol 2015;1:296–305. doi: 10.1001/jamaoncol.2015.0494 - DOI
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- Pan K, Lavasani S, Aragaki AK, Chlebowski RT. Estrogen therapy and breast cancer in randomized clinical trials: a narrative review. Menopause 2022;29:1086–1092. doi: 10.1097/GME.0000000000002021 - DOI
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- Chlebowski RT, Anderson GL, Aragaki AK, et al. Association of menopausal hormone therapy with breast cancer incidence and mortality during long-term follow-up of the Women's Health Initiative randomized clinical trials. JAMA 2020;324:369–380. doi: 10.1001/jama.2020.9482 - DOI
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