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Case Reports
. 2022 Aug 18;10(8):e6227.
doi: 10.1002/ccr3.6227. eCollection 2022 Aug.

Congenital self-healing reticulohistiocytosis: An atypical presentation acquired in a 10-month-old

Christopher S Yuki  1 , Patrick J Young  1 , Steven Ohsie  2 , Xuan Nguyen  3
Affiliations
Case Reports

Congenital self-healing reticulohistiocytosis: An atypical presentation acquired in a 10-month-old

Christopher S Yuki et al. Clin Case Rep. .

Abstract

Congenital self-healing reticulohistiocytosis of Hashimoto and Pritzker (CSHR) is a rare, benign form of Langerhans Cell Histiocytosis (LCH) that presents at birth and involutes by 6 months of age. We present an atypical case of CSHR with the first onset at 7 months of age, treated with surgical excision.

Keywords: CSHR; LCH; dermatology; pathology.

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Conflict of interest statement

The authors have no conflict of interest to declare.

Figures

FIGURE 1
FIGURE 1
06/19/2019. (A) There is a firm, painless, subcutaneous nodule distributed on the right anterior proximal upper arm. H&E‐stained slides (B,C) show a diffuse dermal infiltrate of histiocytoid cells within a background of inflammatory cells including prominent eosinophils. Focal “kidney‐bean” shaped nuclei can be seen (C). The Langerhans cells show positive staining for S100 (D) and CD1a (E). S100 and CD1a are negative in other histiocytic proliferations
See this image and copyright information in PMC

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