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. 2022 Aug 3;9(8):ofac389.
doi: 10.1093/ofid/ofac389. eCollection 2022 Aug.

Prevalence of Medical Contraindications to Nirmatrelvir/Ritonavir in a Cohort of Hospitalized and Nonhospitalized Patients With COVID-19

Sarah Lim  1 , Christopher J Tignanelli  2 , Nicolas Hoertel  3 , David R Boulware  4 , Michael G Usher  4
Affiliations

Prevalence of Medical Contraindications to Nirmatrelvir/Ritonavir in a Cohort of Hospitalized and Nonhospitalized Patients With COVID-19

Sarah Lim et al. Open Forum Infect Dis. .

Abstract

This analysis describes the prevalence of contraindications to nirmatrelvir/ritonavir among 66 007 patients with coronavirus disease 2019 in a large health care system. A possible contradiction was present in 9830 patients (14.8%), with the prevalence of contraindications increasing with higher acuity of illness.

Keywords: COVID-19; Palovid; contraindications; nirmatrelvir/ritonavir.

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Conflict of interest statement

Potential conflicts of interest. D.R.B. has conducted clinical trials of outpatient COVID-19 therapies. Otherwise, the authors declare no conflicts of interest related to this work. The authors: no reported conflicts of interest. All authors have submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest.

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