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Review
. 2022 Oct;22(7):634-641.
doi: 10.1016/j.clbc.2022.07.014. Epub 2022 Aug 5.

Utility of Genomic Platforms in Treatment Decisions in Axilla-Positive Breast Cancer

Isaura Fernández Pérez  1 , Lidia Vázquez Tuñas  2 , Diego Pereiro Corbacho  3 , Carme García Benito  2 , Clara González Ojea  3 , Alberto Garrido Fernández  3 , María José Villanueva Silva  2 , Isabel Lorenzo Lorenzo  2 , Joaquín Casal Rubio  2
Affiliations
Review

Utility of Genomic Platforms in Treatment Decisions in Axilla-Positive Breast Cancer

Isaura Fernández Pérez et al. Clin Breast Cancer. 2022 Oct.

Abstract

Genomic platforms have proven to be more accurate as a prognostic tool than immunohistochemistry studies in patients with early, hormone receptor positive, HER 2 negative breast cancer and, in some cases, have also demonstrated predictive ability for chemotherapy benefit. They are now widely applied in node-negative disease, but their use in node-positive disease is more recent and more controversial, especially in premenopausal patients. In this article, we review the use of these tests in node-positive disease.

Keywords: Genomic platforms, Treatment decisions, Prognostic tool; Luminal breast cancer; Node positive.

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