doi: 10.1007/BF00193899.
Antibodies to the second Epstein-Barr virus nuclear antigen in non-Hodgkin lymphomas
- PMID: 3600498
- DOI: 10.1007/BF00193899
Item in Clipboard
Antibodies to the second Epstein-Barr virus nuclear antigen in non-Hodgkin lymphomas
Med Microbiol Immunol.
1987.
Abstract
Human antibodies against the first and second Epstein-Barr virus encoded nuclear antigens (EBNA-1 and EBNA-2) were analysed by modified ELISA reaction on immunoblots: 5 out of 20 EBNA-1 positive, healthy donor sera reacted with the EBNA-2. Healthy EBV seronegatives contained no antibodies against EBNA-2. The antibodies against this EBNA-2 developed several months after acute EBV infections. Four out of 8 infectious mononucleosis sera failed to react EBNA-2 in the late stage. In the group of EBV seropositive patients with non-Hodgkin lymphoma, 14 out of 18 sera contained EBNA-2 antibodies.
Similar articles
-
Relationship between clinical stage, histopathology and antibody titers against the second Epstein-Barr virus nuclear antigen (EBNA-2) in non-Hodgkin's lymphoma patients.Int J Cancer. 1989 Jun 15;43(6):1017-21. doi: 10.1002/ijc.2910430610. Int J Cancer. 1989. PMID: 2543639
-
Disease-related differences in antibody patterns against EBV-encoded nuclear antigens EBNA 1, EBNA 2 and EBNA 6.Eur J Cancer. 1993;29A(11):1584-9. doi: 10.1016/0959-8049(93)90299-u. Eur J Cancer. 1993. PMID: 8217366
-
Epstein-Barr virus (EBV) antibodies in children with non-Hodgkin's lymphomas.Acta Virol. 1988 Jul;32(4):339-48. Acta Virol. 1988. PMID: 2903639
-
[Malignant lymphoma which contained EBV DNA and lacked EBNA2 antibody].Rinsho Ketsueki. 1989 Jul;30(7):1091-2. Rinsho Ketsueki. 1989. PMID: 2554014 Japanese.
-
Carboxyl-terminal domain of the Epstein-Barr virus nuclear antigen is highly immunogenic in man.Proc Natl Acad Sci U S A. 1985 Sep;82(18):6300-4. doi: 10.1073/pnas.82.18.6300. Proc Natl Acad Sci U S A. 1985. PMID: 2412231 Free PMC article.