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Review
. 2022 Sep;73(9):692-700.
doi: 10.1007/s00105-022-05036-y. Epub 2022 Aug 25.

[Bullous autoimmune dermatoses of the mucous membranes]

[Article in German]
Dario Didona  1 , Julia Hinterseher  2 , Rüdiger Eming  2   3
Affiliations
Review

[Bullous autoimmune dermatoses of the mucous membranes]

[Article in German]
Dario Didona et al. Dermatologie (Heidelb). 2022 Sep.

Abstract
in English, German

Autoimmune bullous diseases (AIBD) comprise a group of organ-specific autoimmune diseases which are characterised by the production of autoantibodies against adhesion molecules and structural proteins of skin and mucosae. Depending on the target protein, AIBD are classified into intraepidermal (pemphigus group) and subepidermal (pemphigoid group, epidermolysis bullosa acquisita, dermatitis herpetiformis) blistering disorders. Depending on the clinical entity, patients can develop blisters, pustules, erosions, and erythema on the skin and mucosae.

Bullöse Autoimmundermatosen (BAID) sind eine Gruppe organspezifischer Autoimmunerkrankungen, die durch die Produktion von Autoantikörpern (AAK) gegen Adhäsionsmoleküle bzw. Strukturproteine der Haut und der hautnahen Schleimhäute verursacht werden. Abhängig von den jeweiligen Zielantigenen der AAK werden intraepidermale (Pemphigusgruppe) und subepidermale (Pemphigoidgruppe, Epidermolysis bullosa acquisita, Dermatitis herpetiformis Duhring) BAID unterschieden. Klinisch zeigen sich je nach Krankheitsentität Vesikulae, Bullae, Pusteln, Erosionen und Erytheme an Haut und Schleimhäuten.

Keywords: Autoantibodies; Blistering skin diseases; Pemphigoid; Pemphigus; Rare skin diseases.

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References

Literatur

    1. Amber KT, Valdebran M, Grando SA (2018) Paraneoplastic autoimmune multiorgan syndrome (PAMS): beyond the single phenotype of paraneoplastic pemphigus. Autoimmun Rev 17:1002–1010 - DOI
    1. Bağcı IS, Horváth ON, Ruzicka T, Sárdy M (2017) Bullous pemphigoid. Autoimmun Rev 16:445–455 - DOI
    1. Bédane C, Doffoel Hantz V (2011) Pemphigoïde cicatricielle: revue de la littérature. Ann Dermatol Venereol 138:201–208 - DOI
    1. van Beek N, Zillikens D, Schmidt E (2021) Bullous autoimmune dermatoses—clinical features, diagnostic evaluation, and treatment options. Dtsch Arztebl Int 118:413–420 - PubMed - PMC
    1. Cozzani E, Di Zenzo G, Gasparini G, Salemme A, Agnoletti AF, Vassallo C, Caproni M, Antiga E, Marzano AV, Cavalli R, Ocella C, de Simone C, Parodi A (2020) Autoantibody profile of a cohort of 54 Italian patients with linear IgA bullous dermatosis: LAD‑1 denoted as a major auto-antigen of the lamina Lucida subtype. Acta Dermatol Venereol 100:adv70