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. 2022 Oct;48(10):1322-1325.
doi: 10.1007/s00134-022-06827-6. Epub 2022 Aug 25.

Physiology of extracorporeal CO2 removal

Luciano Gattinoni  1 , Silvia Coppola  2 , Luigi Camporota  3
Affiliations

Physiology of extracorporeal CO2 removal

Luciano Gattinoni et al. Intensive Care Med. 2022 Oct.
No abstract available

PubMed Disclaimer

Conflict of interest statement

LG reports a consultancy for General Electrics and SIDAM. He also receives lecture fees from Estor and Mindray.

Figures

Fig. 1
Fig. 1
Physiology of ECCO2R: The amount of CO2 removed (VCO2) by the membrane lung is proportional to the gas-flow, the logarithm of extra-corporeal blood-flow; the pre-membrane PCO2 and the membrane lung surface. The sum of the VCO2 of the membrane and the natural lungs, at equilibrium, equals the metabolic VCO2. A reduction in the VCO2 of the natural lung decreases the respiratory quotient (RQ) and, therefore, alveolar PO2 (PAO2). The alveolar nitrogen may decrease if the membrane lung is ventilated with fractions of oxygen higher than those delivered to the natural lung. The decrease of VCO2 of the natural lung allows the decrease in tidal volume and mean airways pressure, which can promote lung collapse
See this image and copyright information in PMC

References

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