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. 2023 Jan;86(1):66-117.
doi: 10.1016/j.jinf.2022.08.018. Epub 2022 Aug 22.

Comparative analysis of transmission and vaccine effectiveness in Omicron and Delta variant outbreaks in China

Kangguo Li  1 , Feng Ruan  2 , Zeyu Zhao  3 , Zhinan Guo  4 , Zimei Yang  1 , Shanshan Yu  1 , Buasiyamu Abudunaibi  1 , Xuebao Zhang  2 , Xiling Yin  2 , Wenhua Mei  5 , Tianmu Chen  6
Affiliations

Comparative analysis of transmission and vaccine effectiveness in Omicron and Delta variant outbreaks in China

Kangguo Li et al. J Infect. 2023 Jan.
No abstract available

Keywords: COVID-19; Epidemiological parameter; VOC; Vaccine effectiveness.

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Conflict of interest statement

Declaration of competing interest The authors declare no competing interests.

Figures

Fig 1
Fig. 1
Vaccination status and epidemiological parameters estimation of infections in COVID-19 outbreaks caused by Omicron BA.2, Omicron BA.1 and Delta. Vaccination status of infections from Omicron BA.2 (A), Omicron BA.1 (B) and Delta (C), respectively, and grouped by age. (D), Fitted serial interval (SI) distribution of paired cases of Delta (n = 83), Omicron BA.1 (n = 31) and BA.2 (n = 19). (E), Fitted incubation period (IP) distribution of cases of Delta (n = 74), Omicron BA.1 (n = 35) and BA.2 (n = 33). (F), The difference between IP and related SI of cases. (G), Fitted probability generation time (GT) distribution of infections of Delta (n = 58), Omicron BA.1 (n = 33) and BA.2 (n = 20). (H), Fitted transmission generation (TG) distribution of infections of Delta (n = 90), Omicron BA.1 (n = 32) and BA.2 (n = 20). (I), Effective reproductive number of difference outbreaks, estimated using R0 package.
Fig 2
Fig. 2
Vaccination status of contacts and vaccine effectiveness against infections in COVID-19 outbreaks caused by Omicron BA.2, Omicron BA.1 and Delta. Vaccination status of contacts from Omicron BA.2 (A), Omicron BA.1 (B) and Delta (C), respectively, and grouped by age. Vaccine manufacturers with contacts in Omicron BA.2 (D), Omicron BA.1 (E) and Delta outbreaks (F), respectively. (G), Comparison of vaccine effectiveness against infection using a logistic regression model. (H), Comparison of vaccine effectiveness against infection using conditional logistic regression model, adjusted for age group.
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References

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