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. 2022 Aug 25;22(1):130.
doi: 10.1186/s12894-022-01086-5.

A new nomogram of urinary flow rate and volume based on multiple measurements per healthy adult Japanese men using a portable uroflowmeter (P-Flowdiary®)

Masatake Shinohara  1   2 , Kazumasa Torimoto  2 , Chie Matsushita  1   3 , Daisuke Gotoh  2 , Hisashi Yoshida  4 , Toshihisa Saka  1 , Yoshihiko Hirao  1 , Akihide Hirayama  5 , Kiyohide Fujimoto  6
Affiliations

A new nomogram of urinary flow rate and volume based on multiple measurements per healthy adult Japanese men using a portable uroflowmeter (P-Flowdiary®)

Masatake Shinohara et al. BMC Urol. .

Abstract

Background: To develop a nomogram of urinary volume and flow based on the data of Japanese men without lower urinary tract symptoms and multiple flows per participant whose characteristics were clear.

Methods: Overall, 101 Japanese male volunteers without lower urinary tract symptoms aged between 20 and 59 years were enrolled. A portable uroflowmeter (P-Flowdiary®) was used to record urinary information (flow rate and volume) for 2 successive days. The model (quadratic, linear, or logarithmic regression) most fit for the relationship between maximum flow rate and voided volume was determined. The maximum flow rate at > 150 mL was compared among the 20-29-, 30-39-, 40-49-, and 50-59-year age groups. Nomograms appropriate for the age groups were created.

Results: The mean age, International Prostate Symptom Score, and Overactive Bladder Symptom Score were 38.5 years, 0.42, and 0.24, respectively. The quadratic regression model was the most fit because its mean coefficient determination was 0.93 ± 0.06. The mean maximum flow rate was significantly lower in the 50-59-year age group (21.8 ± 5.05 mL/s, P < 0.01) than in the younger groups (24.14 ± 4.94, 24.05 ± 6.99, and 24.64 ± 5.72 mL/s). The 2 nomograms are Y = 28.99 {1 - exp(- 0.01 × X)} and Y = 25.67 {1 - exp(- 0.01 × X)} for the 20-49- and 50-59-year age groups, respectively.

Conclusions: The nomogram can predict maximum flow rate based on voided volume in Japanese men aged 20-59 years without lower urinary tract symptoms.

Keywords: Age; Man; Nomogram; Urinary flow rate; Urinary volume.

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Conflict of interest statement

We have no conflicts of interest, but we were involved in the development of P-Flowdiary®.

Figures

Fig. 1
Fig. 1
P-Flowdiary®
Fig. 2
Fig. 2
Representative graphs of the quadratic regression models: A 28-year-old man (R2 = 0.9488) and B 52-year-old man (R2 = 0.9269)
Fig. 3
Fig. 3
Nomograms on voided volume and maximum flow rate: A younger group (20–49 years; mean: 4.92 mL/s) and B older group (50–59 years; mean: 4.04 mL/s), with dark gray area representing ± 1 SD and light gray area representing ± 2 SD
See this image and copyright information in PMC

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